News

CST-103 Improves Brain Blood Flow in Early Clinical Trial

Treatment with the investigational therapy CST-103 increased blood flow to certain regions of the brains of people with Parkinson’s disease and mild cognitive impairment, results of a small clinical trial show. The type of increased blood flow that was seen “correlates with increased neuronal activity and cognitive benefit,” Gabriel…

ATH434 Eases Constipation, Other GI Symptoms in Mouse Model

An investigational therapy, ATH434 was able to reverse some gastrointestinal problems in a mouse model of Parkinson’s disease, according to its developer Alterity Therapeutics. “Practicing clinicians are well aware of the substantial impact that these symptoms have on the quality of life of individuals with Parkinson’s disease,” David Stamler,…

2 Northwestern Researchers Awarded $17.9M in ASAP Grants

Scientists from Northwestern University will use two grants — totaling $17.9 million — from the Aligning Science Across Parkinson’s (ASAP) initiative to study alterations in the brain that contribute to the development of Parkinson’s disease. Their research focuses on brain circuits, the specific populations of interconnected brain cells…

$1.1M NIH Grant Will Further AI-powered Research Analysis

A team of scientists from the University of Florida (UF) will use a $1.1 million grant to further their work on the use of artificial intelligence- or AI-powered medical research for predicting and diagnosing Parkinson’s disease while maintaining patient privacy. This grant, from the National Institutes for Health (NIH),…

FDA Approval Sought to Begin Phase 2 Trial of KM-819

Fascinate Therapeutics has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration (FDA) to initiate a Phase 2 clinical trial evaluating KM-819 as a potential therapy for Parkinson’s disease, the company announced in a press release. Parkinson’s disease is characterized by the death and dysfunction…

FDA Expands Exablate Neuro’s Use as Motor Symptom Treatment

The U.S. Food and Drug Administration has approved Insightec’s incision-free brain “surgery” technology — Exablate Neuro — for the treatment of motor symptoms in Parkinson’s disease patients. According to the company, the device is indicated to use in patients with moderate-to-severe motor complications, such as tremors, stiffness and uncontrolled, involuntary movement…

Fox Takes Stage at ‘A Funny Thing Happened’ Gala

Those attending The Michael J. Fox Foundation’s (MJFF) “A Funny Thing Happened on the Way to Cure Parkinson’s” annual fundraiser got to hear from the organization’s founder, Michael J. Fox. Nearly 700 supporters converged on the Jazz at Lincoln Center in New York City recently to celebrate the…