Author Archives: Marta Figueiredo PhD

Stanford Initiative Focuses on How to Keep the Brain Resilient

A Stanford University research initiative will focus on the causes of neurodegeneration in diseases such as Parkinson’s and on the mechanisms behind some people’s brain resilience to aging and neurodegeneration. This information will be used to find ways to prevent, delay, or even reverse neurodegeneration and cognitive decline. “This…

#AAN2022 – 12 Weeks of Boxing Eases Motor, Non-motor Symptoms

A three-month community-based boxing program significantly eased motor and non-motor symptoms, as well as depression, in adults with early Parkinson’s disease, a pilot study showed. These preliminary findings support larger and longer studies into the benefits of such programs, which also could include people with more advanced disease. Results were…

Oral Enzyme Suppressor ASN90 Shows Promise in Mouse Model

Asceneuron’s experimental oral therapy ASN90 was found to significantly reduce the levels of toxic clumps of the alpha-synuclein protein — a hallmark of Parkinson’s disease — and improve motor function in a mouse model of the disease. The molecule — a suppressor of O–GlcNAcase (OGA), an enzyme involved…

Study Weighs Multidisciplinary Rehab Against Conventional Care

Multidisciplinary rehabilitation for Parkinson’s disease is associated with reduced disability and better functional status and quality of life relative to conventional rehabilitation, according to a review study. However, these differences failed to reach statistical significance. This means that either of the two approaches provide equivalent benefits, or the small number…

VGLUT2 Protein May Protect Neurons From Disease-related Degeneration

A protein involved in the transport of brain signaling molecules may confer protection against neurodegeneration in Parkinson’s disease, a study shows. This transport protein, called vesicular glutamate transporter 2 (VGLUT2), is associated with greater resilience to the toxic effects of alpha-synuclein clumps in dopamine-producing neurons, preventing their death. Dopamine…