XS411, Xellsmart’s experimental stem cell therapy, was generally well tolerated and associated with improved motor function in people with Parkinson’s disease, according to new Phase 1 clinical trial data. The trial (NCT07080775) enrolled nine people with moderate to advanced Parkinson’s. It also showed that the treatment improved…
Discussion
A few weeks ago, a friend of mine took a serious fall while riding a Onewheel around an obstacle course. While lying on the ground, he felt a head-splitting pain. An MRI showed that he had torn his rotator cuff and needed surgery. Before long, I was ushering him to…
Discussion
People with Parkinson’s disease who carry GBA1 variants may experience faster cognitive decline when deep brain stimulation (DBS) is performed later rather than earlier in the disease course, a new study found. “These results should inform shared decision making between clinicians and patients and provide a rationale for prospective…
Discussion
I couldn’t tell you the name of the medication today. But more than a decade later, I can still remember the sound of Uncle Brandon flushing it down the toilet. It was a newer medication his doctor had prescribed for his Parkinson’s disease, and Uncle Brandon hated it. He…
Discussion
Cognitive issues affect about one in three people with Parkinson’s disease, a meta-analysis found, highlighting the importance of early screening and long-term research into the causes and early indicators of cognitive decline in patients. The researchers cautioned that the studies they looked at varied widely in diagnostic criteria and…
Discussion
Remote-monitored home exercise may help people with Parkinson’s disease, but current evidence does not show that it is more effective than standard home exercise or therapist-led rehabilitation, according to a meta-analysis of more than a dozen randomized controlled trials. “It neither establishes an independent effect of remote monitoring nor…
Becoming educated and informed about Parkinson’s is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your Parkinson’s journey.
There is no cure for Parkinson’s yet, but there are treatments that can help manage the disease. Learn more about current therapeutic approaches here.
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