A Phase 2 clinical trial evaluating Avextra’s cannabis-based oral solution’s safety and efficacy in people with Parkinson’s disease and other neurodegenerative disorders has enrolled its first patient. The medicine used in the NEUROBIS (EUCT 2023-507715-35-02) clinical trial is described as a full-spectrum cannabis extract, meaning it contains…
Kneu Health said it has raised $5.6 million to expand its smartphone-based platform that helps doctors monitor symptoms of Parkinson’s disease and other neurological conditions. The company’s platform is a clinically validated tool that tracks changes in movement, speech, and thinking via smartphone. One of its features —…
Deep brain stimulation (DBS) can provide lasting relief from motor symptoms and help people with Parkinson’s disease function better day to day over time, while reducing the need for medication, according to a study led by University of Florida (UF) Health. The new study showed that improvements in…
A new trial platform that will test multiple disease-modifying treatments for Parkinson’s disease is now recruiting participants in the U.K., Cure Parkinson’s has announced. The program, called EJS ACT-PD, will initially test two therapies, telmisartan and terazosin, against a shared placebo. A third treatment, ursodeoxycholic acid, is expected…
Mission Therapeutics has raised $13.3 million to advance MTX325, its treatment candidate for Parkinson’s disease, into a Phase 1b clinical trial in Parkinson’s patients. The funding comes after the company successfully completed a Phase 1a study demonstrating the treatment can enter functional brain tissue in healthy volunteers.
Clario and the University of Oxford are testing a wearable device to see how effective it is at tracking subtle changes in Parkinson’s disease, with the aim of improving clinical research. Clario’s Opal wearable sensor device has demonstrated the ability to detect motor changes faster than traditional clinical…
For the first time, scientists have managed to visualize tiny protein clumps in the brain that are thought to trigger Parkinson’s disease, opening the door for new insights into how the condition develops. In a study detailing their work, the team presented an imaging method able to “generate large-scale…
Shape Therapeutics’ SHP-201, an experimental gene therapy for Parkinson’s disease, significantly reduced the levels of alpha-synuclein — a protein that plays a key role in the development of the neurodegenerative condition — in the brain of mouse and nonhuman primate models, according to new preclinical data released by…
WTX-607, an oral small molecule being developed by Wavebreak, binds to and blocks the formation of small alpha-synuclein protein clumps — toxic aggregates linked to nerve damage in  Parkinson’s disease and Lewy body dementia — in human brain tissue, according to new data released by the company. The…
An experimental therapy being developed by Herantis Pharma for Parkinson’s disease was well tolerated and able to penetrate the blood-brain barrier (BBB), a semipermeable membrane that prevents certain substances, including medications, from entering the brain. That’s according to top-line data from a Phase 1b trial (NCT06659562), which…
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