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Brain imaging data are not very useful for computer models predicting the long-term trajectory of Parkinson’s disease, a study showed. Researchers found that computer models aimed at predicting Parkinson’s progression were not meaningfully better when imaging data were included. In fact, some models became less accurate when imaging data…

Starting rehabilitation within the first year after a Parkinson’s disease diagnosis may be associated with longer survival, even among people who had already developed disability, a nationwide South Korean study found. Delaying rehabilitation was associated with progressively higher mortality risk across all disability levels, including among people without functional…

People with depressive symptoms may have higher odds of developing Parkinson’s disease, a large study suggests, with the researchers noting a potentially greater risk among those with stronger genetic susceptibility to the neurological condition. The findings also point to changes in fat metabolism — one of several “metabolic disturbances”…

People with Parkinson’s disease who experience visual hallucinations have reduced activity in the brain’s cholinergic system, a network of nerve cells that use the chemical messenger acetylcholine, a brain imaging study found. Impaired cholinergic signaling in certain brain regions early on predicted who would later develop visual hallucinations. The…

Remepy has raised $36 million in financing, which the company will use in part to fund a late-stage clinical trial testing Hybridopa, its novel treatment strategy for Parkinson’s disease that combines medication with a mobile application. With these funds in hand, the New York-based Remepy expects to launch…

Changes in gut bacteria may be linked to Parkinson’s disease and can vary with age, disease severity, and medications, but more research is needed to understand whether these changes actually contribute to how symptoms develop and progress, a study suggests. “These findings regarding the relationships between microbial communities…

Higher levels of physical activity are associated with slower worsening of certain motor symptoms and better preservation of certain measures of cognitive function in people with Parkinson’s disease, according to a recent study. People who were more physically active also showed a slower decline in…

Neuralight’s eye-movement biomarkers may predict declines in daily functioning in people with Parkinson’s disease before those changes can be detected by conventional clinical assessments, new clinical study data suggest. The…

Practicing Tai Chi four times a week may lessen motor symptoms and improve physical function and quality of life in people with early- to mid-stage Parkinson’s disease, a small clinical trial found. A program combining resistance and stretching exercises produced similar overall improvements in motor symptoms, but each approach…

The U.S. Food and Drug Administration (FDA) has awarded fast-track designation — a status that aims to speed the development of promising treatments for serious conditions — to a Swiss biopharmaceutical company for an experimental vaccine designed to slow or prevent neurodegeneration in people with early Parkinson’s disease. The…