Margarida Maia, PhD, science writer —

Acting out a word or phrase may help people keep memory of it — a phenomenon called the enactment effect — and this also may hold true for those with poor motor control due to Parkinson’s disease, according to a review study. “Our meta-analysis found that even Parkinson’s disease…

A non-invasive skin swab test may make a diagnosis of Parkinson’s disease in as few as three minutes, according to a study done at The University of Manchester in the U.K. The test looks at samples of sebum, an oily matter made by glands in the skin, where it can…

IMAC Holdings has completed the dosing of a third and last group of patients who are taking part in a Phase 1 clinical trial that’s testing an investigational stem cell therapy for bradykinesia due to Parkinson’s disease, the company announced. Five patients received a one-time intravenous…

Patient dosing has begun in a Phase 2a clinical trial testing oral CST-2032 in combination with CST-107 as a potential way to ease the symptoms of mild cognitive impairment and mild dementia due to Parkinson’s or Alzheimer’s disease, the company developing these therapies, CuraSen Therapeutics, announced. The trial (…

The first patient has been dosed in a clinical trial testing Annovis Bio’s buntanetap as an oral therapy for early-stage Parkinson’s disease, the company announced. The Phase 3 clinical trial (NCT05357989) got started shortly after the U.S. Food and Drug Administration (FDA) gave the company the…

Deep brain stimulation (DBS) may not put people with advanced Parkinson’s disease at a greater risk of excessive drooling, a common non-motor symptom also known as sialorrhea, according to a yearslong study of patients by researchers in Italy. Male sex, difficulty swallowing (dysphagia), and more severe disease, however, were…

Certain genetic mutations may help determine the length of survival in Parkinson’s disease patients, according to findings by a team of researchers from four institutes in Paris. Patients with Parkinson’s who carried a mutation in either the LRRK2 or the PRKN genes were found to live longer than those…

Antibodies against certain components of the renin-angiotensin system (RAS), which helps to control blood pressure, are present at higher levels in people with Parkinson’s than in those without the disease and may drive progression, a study found. These elevated levels of autoantibodies — which make nerve cells more vulnerable…

About 1 in 3 Parkinson’s disease patients in two Phase 3 trials experienced an “off” episode before going to sleep, and most of those who woke up during the night were in an “off” state upon awakening, researchers reported. These findings were pulled from a new analysis of data obtained…

Stem cells in the lab were turned into nerve cells (neurons) that can make dopamine — the chemical that is lacking in patients with Parkinson’s disease — and transferred into the brain of rats with a form of parkinsonism, where they worked to restore lost motor function, a study…