Author Archives: Margarida Maia

EMA Says No to Nouryant for Marketing Approval in Europe

A committee of the European Medicines Agency (EMA) is recommending the refusal of marketing authorization for Nouryant (istradefylline) — approved as Nourianz in the U.S. — as a medication for treating off episodes in Parkinson’s disease in the EU. In its opinion, the Committee for Medicinal Products for Human…

Turmeric Oil Derivatives May Help to Protect Dopaminergic Neurons

A compound naturally found in turmeric essential oil, called aromatic turmerone (ar-turmerone), and its derivatives were seen to protect dopaminergic neurons in a tissue culture model of Parkinson’s, researchers report. These findings support the already known role of ar-turmerone in reducing the inflammatory response caused by activated microglia —…

Dancing May Improve Motor and Non-motor Symptoms

Training to dance to music on a weekly basis may slow the progression of both motor and non-motor symptoms of Parkinson’s disease, a three-year study has found. Results from this pilot study suggest that dance training could be used as a strategy to slow the progression of Parkinson’s in…

Smoking History May Not Be Linked to Parkinson’s

Smoking history may not influence the severity of symptoms in Parkinson’s disease, a small study suggests. Moreover, in some individuals, exposure to cigarette smoke may worsen motor symptoms, which could lead patients to quit smoking and explain why smoking is more common among people without the disease. The study,…

Caraway, AbbVie Ink Deal to Develop TMEM175-targeting Therapies

Caraway Therapeutics is partnering with AbbVie to develop and market Caraway’s small molecule therapies targeting TMEM175, a potassium ion channel implicated in Parkinson’s disease and other neurodegenerative disorders. TMEM175 is present in lysosomes — tiny compartments in cells containing enzymes that break down unwanted cell parts, digesting and…

Patient Willingness to Skip Flu Shots May Be Issue for COVID Vaccines

A considerable number of people with Parkinson’s disease living at home missed every flu vaccination given over five years despite being at higher risk of preventable respiratory infections, a single-site U.S. study of homebound and ambulatory patients found. Nearly 25% of these patients also expressed hesitancy about vaccines, and…

CEPT Cocktail Protects Stem Cells in Lab, Opening Research Possibilities

A four-ingredient, small-molecule cocktail was seen to protect stem cells from the stresses of lab work better than existing agents, helping to preserve their normal structure and function, researchers reported. This cocktail may overcome the “daunting challenge” of keeping pluripotent stem cells viable, so to be more useful in research into stem…