One month of a high-dose nicotinamide riboside (NR) supplement — thought to boost energy production in the body’s cells — was well-tolerated and eased motor symptoms among people with Parkinson’s disease in a small clinical trial. But the researchers caution that these results are preliminary, and note that data…
Scientists have developed a handheld device that can be used to measure levels of biomarkers for Parkinson’s disease and other neurological disorders. “This portable diagnostic system would allow testing at-home and at point of care, like clinics and nursing homes, for neurodegenerative diseases globally,” Ratnesh Lal, PhD, said in…
When an advanced treatment for Parkinson’s disease such as deep brain stimulation (DBS) stops working, changing treatments or adding a new treatment often can help control disease symptoms, a new study reports. “Based on the results of our study, we can now make a clear recommendation for action. If…
Bifidobacteria, a type of bacteria found at higher levels in the gut of Parkinson’s disease patients, is capable of breaking down levodopa, the gold-standard therapy for the neurodegenerative disease, according to recent laboratory studies. Levels of the bacteria in the guts of Parkinson’s patients correlated with the dose of…
Andrés Bratt-Leal, a co-founder of Aspen Neuroscience who is leading work there on a potential stem cell therapy for Parkinson’s disease, is among the recipients of the 2023 Life Science Catalyst Award given to young scientists and entrepreneurs in recognition of their contributions. Sponsored by…
Some molecular changes that drive damage to brain cells in Parkinson’s disease take place in skin cells too, a study has found, adding to evidence that examining the skin may support an early diagnosis. Because skin cells are much easier to collect than brain cells, they also could be…
The first patient has been dosed in a Phase 2 clinical trial testing AC Immune’s ACI-7104.056, an investigational vaccine targeting toxic alpha-synuclein forms to prevent nerve cell degeneration in Parkinson’s disease. AC Immune expects to complete the enrollment of the first group of patients in the VacSYn…
The Institute for Glial Sciences, a center dedicated to the role of glial cells in Parkinson’s disease and others affecting the nervous system with a goal of better treatments, is opening at Case Western Reserve University in Ohio. It will be led by Paul Tesar, PhD, a professor in…
U.K. scientist Dario Alessi, PhD, has been named the winner of the 2023 Robert A. Pritzker Prize for Leadership in Parkinson’s Research — awarded annually by the Michael J. Fox Foundation (MJFF) to a researcher who makes exceptional contributions in the field of Parkinson’s disease and seeks…
Buntanetap significantly reduced the levels of TDP-43 protein in the blood of people with Parkinson’s disease who participated in a Phase 2a clinical trial, according to clinical data from its developer Annovis Bio. The treatment also demonstrated a trend toward reducing other markers of inflammation. “We are pleasantly…
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