News

Stanford Initiative Focuses on How to Keep the Brain Resilient

A Stanford University research initiative will focus on the causes of neurodegeneration in diseases such as Parkinson’s and on the mechanisms behind some people’s brain resilience to aging and neurodegeneration. This information will be used to find ways to prevent, delay, or even reverse neurodegeneration and cognitive decline. “This…

UB-312 Vaccine Well Tolerated by Healthy Adults in Ongoing Trial

UB-312, an experimental vaccine targeting aggregated and toxic forms of alpha-synuclein to treat Parkinson’s disease, was generally well tolerated at multiple doses in a clinical trial in healthy adults. Study data also suggest that UB-312 prompted an immune response, as designed, against the alpha-synuclein protein. With two doses now selected…

Peripheral Neuropathy Can Be Evident, Levodopa Link Possible

Damage to certain nerve fibers in the extremities, known as peripheral neuropathy, was evident in some people with Parkinson’s disease, including those at early disease stages, a study reported. Findings in this work, which used a sensitive electrophysiological device to examine nerves, also suggested that peripheral neuropathy was related…

MJFF Names WCG as Review Board for Large PPMI Biomarker Study

WCG IRB will now serve as the institutional review board (IRB) for the Michael J. Fox Foundation’s (MJFF) ongoing Parkinson’s Progression Markers Initiative (PPMI) study, WCG announced. The PPMI study (NCT04477785), renamed PPMI 2.0 in July 2020, is a longitudinal, observational study of individuals with and without…

AI Platform Shows Potential in Diagnosing Patients at Early Stages

PreciseDx’s artificial intelligence (AI) platform shows an ability to accurately diagnose Parkinson’s disease in people before they develop severely evident symptoms, according to a new study. Conducted in collaboration with The Michael J. Fox Foundation (MJFF), the study’s findings support the platform’s potential to aid in diagnosing Parkinson’s and allowing patients to begin…

Researchers Target MRI as Diagnostic Biomarker

A research team in Canada is embarking on a project that will apply MRI to identify new biomarkers for diagnosing Parkinson’s disease and monitoring its progression over time. The potential findings may speed Parkinson’s diagnoses and help patients receive treatment sooner. Identifying easily recognizable MRI signatures of Parkinson’s could…

#AAN2022 – 12 Weeks of Boxing Eases Motor, Non-motor Symptoms

A three-month community-based boxing program significantly eased motor and non-motor symptoms, as well as depression, in adults with early Parkinson’s disease, a pilot study showed. These preliminary findings support larger and longer studies into the benefits of such programs, which also could include people with more advanced disease. Results were…