An experimental molecule called ONO-2506 was found to reduce the occurrence of abnormal movements — dyskinesia — resulting from early levodopa treatment without compromising levodopa’s therapeutic effects in a rat model of Parkinson’s disease. The mechanisms by which ONO-2506 was able to ease levodopa-induced dyskinesia (LID) appeared…
Several people with Parkinson’s disease were able to improve their ability to walk by using a “wearable cyborg” over their torso, a study reports. The study, “Gait improvement with wearable cyborg HAL trunk unit for parkinsonian patients: five case reports,” was published in Scientific Reports. The work…
A 12-week virtual music therapy program was found to reduce apathy and depression among people with Parkinson’s disease — and to help ease feelings of burden for their caregivers, a new study reported. “Group music therapy is an effective treatment for apathy in PD [Parkinson’s disease] and may improve…
At an upcoming free webinar, hosted by Synapticure, experts will discuss how the chemical trichloroethylene or TCE — a widely-used solvent now well known to have toxic side effects — may be a cause of Parkinson’s disease. The webinar, “TCE: An Invisible Cause of Parkinson’s,” is taking place via…
Anxiety is a common problem for people with Parkinson’s disease and can cause substantial difficulties in patients’ day-to-day lives, a new study based on patient interviews highlights. In some cases, anxiety can be more of a problem than motor symptoms: “I would put up with some of the…
Researchers have identified certain pesticides used in agricultural settings that were linked to Parkinson’s disease risk among people living in California — and that were toxic to nerve cells in laboratory studies. Particularly, a pesticide called trifluralin was a significant driver of nerve cell toxicity, an effect that was…
To help offset the lack of specialty care in Parkinson’s disease, the Parkinson’s Foundation is offering providers who aren’t experts in the progressive neurodegenerative disorder access to the virtual course, “Utilizing Quality Measures to Improve Parkinson’s Care: What Every Neurologist Needs to Know.” The course, which is…
Inhibikase Therapeutics, which is recruiting up to 120 untreated Parkinson’s disease patients across the U.S. to test its oral therapy IkT-148009, announced that its 201 trial program just dosed its first participant. The Phase 2 trial (NCT05424276) is assessing the safety and tolerability of IkT-148009 versus a…
The risk of Parkinson’s disease is increased among people who have been exposed to the chemical trichloroethylene (TCE), according to a new analysis of U.S. military personnel. The study, “Risk of Parkinson Disease Among Service Members at Marine Corps Base Camp Lejeune,” was published in JAMA…
BioVie is exploring a potentially pivotal Phase 3 clinical trial to test its experimental oral therapy NE3107 in people with Parkinson’s disease. “Throughout the past several months, data reported or presented at major medical conferences have established a compelling rationale for further clinical evaluation of NE3107 in Parkinson’s Disease,”…
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