Physical exercise eased signs of a type of iron-mediated cell death called ferroptosis in microglia and improved neurological function in mouse models of Parkinson’s disease, a study finds. Microglia are a type of nervous system support cell that’s believed to be important in the neurodegenerative disease. When ferroptosis was…
The Michael J. Fox Foundation (MJFF) has brought together top experts from around the world to speed up research on five lesser-known biological targets in Parkinson’s disease in an effort to identify promising treatment opportunities. Seven more will be explored in a future phase. This effort is part…
NDC-0524, an experimental antibody that Nitrase Therapeutics is developing as a treatment for people with Parkinson’s disease, is expected to enter clinical testing in the fourth quarter of 2025, or before the end of the year, according to a company press release. The antibody, which targets nitrated…
Newronika is preparing for the commercial launch of AlphaDBS — a next-generation adaptive deep brain stimulation (DBS) system for treating Parkinson’s disease — at selected markets in Europe this year, following CE Mark approval in the European Union. That’s according to a company press release, in which…
Neuropacs‘ MRI-based artificial intelligence (AI) technology demonstrated 96% accuracy in distinguishing Parkinson’s disease from atypical parkinsonism — including multiple system atrophy, known as MSA, and progressive supranuclear palsy, called PSP — the company announced, detailing the results of a federally funded U.S. study. Moreover, the system achieved 98%…
Parkinson Italia — a network of 30 associations for patients and caregivers in Italy — is backing an initiative by the Prada Foundation that seeks to highlight the importance of prevention and early treatment of neurodegenerative diseases like Parkinson’s. The campaign, dubbed Preserving the Brain: A…
Parkinson’s disease can lead to early retinal changes — alterations in the thin layer at the back of the eye, known as the retina, that’s responsible for detecting light and sending visual signals to the brain — that can be revealed with the use of a simple eye test,…
Most people with early-stage Parkinson’s disease have sleep disturbances, with many having more than one at the same time, a study in France suggests. Sleep disorders were mainly associated with body changes, including motor symptoms and problems regulating involuntary bodily functions, rather than depression or anxiety. “The timely…
Angels on Call, a home care services provider, has been recognized as a Community Partner in Parkinson’s Care by the Parkinson’s Foundation. The Community Partner in Parkinson’s Care membership program educates and trains staff to deliver care plans specifically focused on Parkinson’s patient’s symptoms and…
Researchers for the first time visualized how PINK1, a protein linked to early-onset Parkinson’s disease, binds to mitochondria and how it’s switched on to protect these energy-producing structures when they’re damaged. Using a high-resolution microscope to map the structure of the human version of PINK1 bound to damaged mitochondria,…
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