People with Parkinson’s have postural adjustments even at early stages of the disease when clinical symptoms of postural instability are not evident and despite the use of antiparkinsonian medications, a recent study shows. Researchers believe these findings suggest that postural behavior may be used as an early indicator to…
Subtle changes in the levels of Alzheimer’s disease biomarkers in patients at the earlier stages of Parkinson’s disease may provide clues about the evolution of their motor and cognitive functions, a study says. The study, “Evolution of Alzheimer’s Disease Cerebrospinal Fluid Biomarkers in Early…
Scientists have discovered, for the first time, that patients with Parkinson’s disease have a much greater number of opportunistic disease-causing microbes living in their gastrointestinal tract, compared to people without the disease. Further studies are needed to determine if these opportunistic microorganisms may be involved directly in the onset…
Multiple administrations of Affitope PD01A, an investigational vaccine for Parkinson’s disease, elicit a safe and sustained immune response against alpha-synuclein — a protein involved in the development of Parkinson’s — in patients at the early stages of the disease, according to results from a Phase 1…
A new dietary silicon-based antioxidant agent prevented neurodegeneration, and motor balance and coordination problems, in a mouse model of Parkinson’s disease. By promoting production of the antioxidant molecule hydrogen, the agent  also was shown to prevent kidney failure in a rat model of chronic kidney disease, another…
Sedentary behavior during waking hours is linked to poorer attention spans in people with mild to moderate Parkinson’s disease, a small pilot study in patients reports. The study, “Sedentary Time is Associated with Worse Attention in Parkinson’s Disease: A Pilot Study,” was published in the Journal…
Older men who have a weak or irregular circadian rhythm — the body’s internal clock that controls the sleep-wake cycle — are approximately three-times more likely to develop Parkinson’s disease later in life, compared to those who have regular activity-rest cycles, a study has found. According to researchers,…
An infusion of levodopa/carbidopa to the intestines may be a therapeutic option for Parkinson’s disease patients who develop freezing of gait following deep brain stimulation, according to a recent study. The study, “Intestinal Levodopa/Carbidopa Infusion as a Therapeutic Option for Unresponsive Freezing of Gait after…
New magnetic resonance imaging (MRI) techniques capable of zeroing in on a pea-size region of the brain responsible for movement control may allow physicians to treat patients with Parkinson’s disease or essential tremor without having to resort to invasive brain surgery. These methods were described in the…
Coenzyme Q10, an antioxidant supplement that, when taken orally, has shown limited effectiveness, can alleviate Parkinson’s disease symptoms when injected directly into the brain, a study in rats suggests. The study, “Intrastriatal administration of coenzyme Q10 enhances neuroprotection in a Parkinson’s disease rat model,”…
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