Excess Alpha-synuclein Directly Linked to Mitochondrial Problems
Higher-than-normal levels of alpha-synuclein — the protein that accumulates in toxic clumps in Parkinson’s disease — affect the shape, dynamics, and health of mitochondria, which are the powerhouses of the body’s cells, according to a study in a fruit fly model. “When fruit fly larvae expressed alpha-synuclein at elevated…