“Parkinson’s Science POV,” a limited series podcast by The Michael J. Fox Foundation for Parkinson’s Research (MJFF), has garnered silver and Listener’s Choice honors at the Signal Awards’ inaugural program. The awards, honoring top 2022 podcasts globally, recognized the Parkinson’s disease series within its Science & Education category for “Limited Series…
Scientists have identified potential biomarkers for the early detection of Parkinson’s disease in certain people carrying a common disease mutation. Specifically, they found that a combination of four small RNA molecules, called microRNAs (miRNAs), in the blood may help predict disease onset in people who carry a Parkinson’s-associated LRRK2…
IntelGenx has teamed up with a renowned neurologist at the Karolinska Institute, Sweden to conduct a clinical trial on Montelukast VersaFilm, its proprietary oral thin film formulation, in people with Parkinson’s disease. The multicenter trial, expected to start between July and September, will be led by Per Svenningsson,…
The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has awarded a $2.5 million research grant to advance the development of Soturi, Newel Health’s digital therapeutic app designed to help patients optimize their personalized treatment plan. The Soturi app is designed to deliver services to people with…
A Phase 3 clinical trial of Annovis Bio‘s investigational oral treatment buntanetap in people with early-stage Parkinson’s disease now will open to patients in Europe. This expansion will add 48 new trial sites in Italy, Spain, Hungary, Poland and Germany, joining about 50 sites actively recruiting in the U.S.
Mindfulness meditation — a mental training of being focused on the present moment without interpretation or judgment — was better than physical exercise at lessening depression symptoms and maintaining emotional stability in people with mild-to-moderate Parkinson’s disease. That’s according to data from a small clinical trial conducted in Hong…
AC Immune has been awarded two research grants to identify the presence of TDP-43, a protein that plays a key role in neurodegeneration underlying Parkinson’s disease and other neurological diseases. The grants were awarded by the Michael J. Fox Foundation for Parkinson’s Research (MJFF) and Target…
Dosing has begun in a Phase 1 clinical trial of healthy volunteers to evaluate the safety and pharmacological properties of NEU-723, Neuron23’s oral investigational treatment for Parkinson’s disease. The small molecule candidate therapy is designed to block LRRK2, an enzyme coded by a gene of the same name whose…
People with REM sleep behavior disorder (RBD), a sleep disturbance that can precede Parkinson’s disease, have higher levels of toxic alpha-synuclein protein clumps in their stool than do Parkinson’s patients and healthy people, a study showed. Alpha-synuclein aggregates, toxic to cells, are thought to contribute to Parkinson’s and other…
Microglia — the brain’s primary immune cells — can help to keep motor symptoms of Parkinson’s disease from quickly advancing in early disease stages, work in a mouse disease model suggests. Its findings support studies indicating both a neuroprotective and damaging role for these immune cells over the disease’s…
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