Exposure to alpha-synuclein, a protein that accumulates in the brains of Parkinson’s disease patients, led to inflammation and damage to nerve cells in the gut of mice carrying a human gene associated with several autoimmune disorders, a new study showed. Alpha-synuclein-related autoimmunity also induced constipation — a gut-related…
Racial disparities exist in the use of deep brain stimulation among people with Parkinson’s disease, a real-world claims study concluded. Compared to the proportion represented in the Medicare database, more people who identified as white, and fewer Black and Hispanic patients, underwent deep brain stimulation (DBS) for Parkinson’s.
Medications commonly used in the treatment of Parkinson’s disease may affect the body’s ability to control its core temperature, part of the body’s so-called automatic functions, which include sweating, a review study found. Such agents — which include anticholinergic medications and cholinesterase inhibitors, dopamine replacement therapies, and dopamine…
Problems in quality control processes that support the health and function of mitochondria, crucial for cellular energy, are evident in nerve cells of people with Parkinson’s disease, a study showed. Mitochondrial recycling and protein balance were particularly impaired, which may impede energy production and lead to the early nerve…
The COVID-19 pandemic has had some negative physical and social impacts on the overall well-being of people with Parkinson’s disease, a new study highlights. Therefore, it’s important for clinicians to help patients get social support, not just address physical symptoms of the disease as pandemic-related restrictions ease, researchers wrote…
Rates of Parkinson’s disease progression and treatment response may differ among patients depending on whether the disease primarily affects the dominant or nondominant side of the body, a small study of typing skills in patients new to dopaminergic therapy suggests. “These findings suggest that the relationship between side of…
The Parkinson’s Solutions Summit, to be presented online from Nov. 14-20, will provide tips and practical actions to help Parkinson’s disease patients and caregivers better cope with the progressive neurodegenerative disorder. The free event will be presented by DrTalks, a platform that aims to empower people through…
Regular physical exercise helps to improve balance and mobility in people with mild to moderate Parkinson’s disease, an analysis of published studies reports. Best results, in terms of this easing in disease motor symptoms, were seen with “consistent and sustained” participation in exercise sessions. “The findings of our…
Researchers in Oregon will be the first to incorporate Koneksa’s digital tools in a Parkinson’s disease study comparing two formulations of levodopa: immediate-release versus extended-release pills. By joining the Koneksa Academic Partnership Program for Parkinson’s Disease (KAPP-PD), the researchers will gain access to a neuroscience toolkit that…
A headset developed by MindRhythm was able to pick up abnormal brain changes that outlasted by two weeks the symptoms of a concussion in young Australian rules football players, a study reports. The information could be used to decide if an athlete is ready to play again after a…
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