UB-312, an experimental vaccine by Vaxxinity, appeared safe and well tolerated and was able to produce an immune response against toxic alpha-synuclein protein aggregates in people with early Parkinson’s disease, according to data from a clinical trial. According to the company, UB-312 met the primary objectives of the…
Following a positive safety review, Annovis Bio‘s Phase 3 clinical trial testing oral buntanetap for the treatment of early-stage Parkinson’s disease can move forward as originally designed, the company announced. That positive review came from the Data and Safety Monitoring Board (DSMB), an independent group of experts, which…
A history of using inhaled beta-2 adrenoceptor (B2AR) agonists to treat asthma or chronic obstructive pulmonary disorder (COPD) was not associated with a decreased risk of developing Parkinson’s disease, according to a recent Finnish study. The findings contrast earlier epidemiological studies that found these medications, commonly used to treat…
Following promising new data from healthy volunteers in early clinical trials, NodThera now is testing its oral treatment candidate NT-0796 in a Phase 1b/2a biomarker study involving people with Parkinson’s disease. The biotech company announced the positive results from its first-in-human Phase 1 study (ACTRN12621001082897), which found…
People with Parkinson’s who smoke cigarettes or use aspirin tend to report more problems with certain disease symptoms, according to a new study. The study, however, did not find notable associations between drinking coffee and Parkinson’s symptom severity. “This study comprehensively assesses the effect of smoking, coffee drinking, and aspirin…
A framework set up by the Parkinson’s Foundation can help therapists and other professionals design more personalized exercise programs for people with Parkinson’s disease. The competency framework, as it is called, outlines programs, courses, and approaches that help to educate and train movement specialists, given the…
Axial Therapeutics will use a new research grant from the Michael J. Fox Foundation for Parkinson’s Research (MJFF) to advance its experimental therapy for Parkinson’s disease, AX-5006, from ongoing preclinical studies into a first clinical trial in humans. The company is conducting a series of preclinical studies…
People with Parkinson’s disease who are experiencing cognitive decline may show weaker low-frequency brain waves on an electroencephalogram (EEG), a recording of the brain’s electrical activity, according to a recent study. Brain waves recorded at the front part of the brain were linked to measures of cognitive decline and…
Koneksa has partnered with Beacon Biosignals to launch a clinical trial focused on advancing research in neuroscience, including Parkinson’s disease, with an aim to develop electroencephalogram (EEG) biomarkers. EEG technology has long been used to measure the brain’s electrical activity and identify evidence of neurological disorders like…
Programs focusing on traditional forms of Brazilian dance may help to improve life quality and ease motor symptoms for people with Parkinson’s disease, a new study reports. “The findings of this study suggest that Brazilian dance practice is capable of improving the perception of some aspects of quality of life…
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