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MJFF grant will aid Stealth’s study of mitochondrial biomarkers

A grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) will support a two-year preclinical study by Stealth Biotherapeutics to evaluate its investigational therapy SBT-272, a small molecule designed to target cells’ mitochondria. The study is intended to identify biomarkers of mitochondrial dysfunction, a phenomenon often…

Dopamine neurons may be more diverse than thought

A specific subset of dopamine-producing nerve cells in the brain appear to respond to movement acceleration and correspond with the region where cell death is particularly pronounced in Parkinson’s disease, according to a recent study. These neurons were responsive only to movement, and not to rewarding stimuli, which long…