News

Sensors may allow at-home measuring of levodopa levels

Researchers have created a system that could be developed to allow at-home measuring of levodopa levels in people with Parkinson’s disease. The system was described in the study “Smartphone-based detection of levodopa in human sweat using 3D printed sensors,” published in Analytica Chimica Acta.

Cell therapy bemdaneprocel safe in advanced Parkinson’s: Phase 1 trial

Treatment with bemdaneprocel (BRT-DA01), BlueRock Therapeutics’s investigational cell-based therapy, was safe and well tolerated among patients with advanced-stage Parkinson’s disease, according to top-line results from a Phase 1 clinical trial. Furthermore, data also showed that transplantation was feasible, and there was evidence of cell survival and engraftment in…

Parkinson’s Foundation expands specialized care network

The Parkinson’s Foundation has expanded its Global Care Network by adding four Centers of Excellence and four Comprehensive Care Centers to increase access to specialized multidisciplinary care for people with Parkinson’s disease. This expansion recognizes centers within a broad geographic region, including the first-ever designations in Wisconsin,…

Researchers develop tool to study gut-brain connection

Researchers have uncovered new evidence that activity in the gut can directly influence brain function, a relationship that’s been proposed to contribute to Parkinson’s disease. Using specialized fibers with the ability to stimulate nerve cells with light, called optogenetics, the scientists found that by altering cell activity in the…

Potential gene therapy may help with GBA1-linked Parkinson’s

Freeline Therapeutics announced plans to leverage knowledge gained from its FLT201 gene therapy program in Gaucher disease to advance a similar candidate to treat people whose Parkinson’s is tied to mutations in the GBA1 gene. “Our GBA1-linked Parkinson’s disease program is a natural extension of our…

3 blood biomarkers might identify Parkinson’s, atypical parkinsonism

Certain biomarkers in the blood may help doctors in determining whether a person has Parkinson’s disease or atypical parkinsonism, both of which show similar symptoms, a study reported. Three biomarkers — neurofilament light chain (NfL) and malondialdehyde (MDA), particularly, but also 24S-hydroxycholesterol (24S-HC) — were found at significantly…

DBS helps grandfather, 77, struggling with Parkinson’s off times

Carl McLain, a grandfather and Parkinson’s disease patient, reports enjoying a much-improved quality of life since undergoing deep brain stimulation (DBS), a surgical treatment generally advised for those failing to respond to other disease therapies. McLain 77, said he began experiencing mysterious leg pain, anxiety, depression, and…