Continuous exposure to low-oxygen air halted neurodegeneration and eased or reversed motor symptoms in a mouse model of Parkinson’s disease, a study reports. “The results raise the possibility of an entirely new paradigm for addressing Parkinson’s,” Fumito Ichinose, MD, PhD, senior coauthor of the study, said in a…
ENERGI-F705PD, a potential disease-modifying therapy for Parkinson’s disease, was found to be safe and well tolerated in a Phase 1 clinical trial involving healthy volunteers, according to developer Energenesis Biomedical. Unlike currently available treatments, ENERGI-F705PD aims to address the causes of Parkinson’s and not just its symptoms.
Lysoway Therapeutics has received a $2.93-million grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF). The funding will advance a potential new therapy that targets the TRPML1 protein, a promising approach designed to modify the disease’s progression rather than just treating symptoms. “This funding underscores growing…
The Parkinson’s Foundation has awarded more than $1 million in community grants to fund dozens of local programs that support mental health, exercise, and education in Parkinson’s disease across 38 U.S. states, as part of its ongoing efforts to help patients live better lives. Ninety local programs…
People with Parkinson’s disease who live in disadvantaged communities tend to have more severe motor symptoms and greater motor disability, according to a study that shows that social and environmental factors, many of which may be modifiable, can influence the severity of the disease. “If environmental exposures or other…
Using mathematical models, researchers at the University of California, San Francisco (UCSF) successfully predicted how to adjust deep brain stimulation (DBS) settings to improve gait for people with Parkinson’s disease, according to a study. With these techniques, researchers could improve DBS and other neuromodulatory therapies that influence nerve…
When combined with deep brain stimulation (DBS), a dynamic, cycling-based exercise program for people with Parkinson’s disease produces changes in brain activity indicative of potential neural rewiring, according to a study. The research was conducted at University Hospitals in Cleveland and the Veterans Affairs Northeast Ohio Healthcare System,…
Infection with a common and otherwise harmless virus called human pegivirus (HPgV) might play a hidden role in Parkinson’s disease, particularly for those with specific genetic risks, according to a new study. “For a virus that was thought to be harmless, these findings suggest it may have important effects,…
Neu Health is launching its smartphone-based system to measure tremors in people with Parkinson’s disease in the U.S. The Food and Drug Administration (FDA) has cleared the company’s digital tool to track Parkinson’s symptoms remotely, which uses only a smartphone to measure tremor severity, reducing reliance on wearables…
Researchers have uncovered how exposure to a common environmental pesticide may disrupt brain function in ways that contribute to Parkinson’s disease. Exposing rats to rotenone, a pesticide mostly banned in the U.S. and Canada, but still used in lake management, triggered changes in the activation of certain genes in…
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