News

Once-daily treatment with opicapone provides continued reductions of off periods in Parkinson’s patients taking levodopa, a Phase 3 clinical study shows. The findings also reveal that opicapone’s effectiveness was superior to that of Comtan (entacapone, marketed by Novartis). The results were presented in three scientific posters at the 2018 World…

A fish that can sense the Earth’s magnetic field while it swims could help scientists understand how the human brain works and eventually unlock strategies to help control movement impairments in patients with Parkinson’s disease and other neurological disorders, a study reports. The study, “Wireless control of cellular function by…

Long-term daily use of Ingrezza (valbenazine) leads to a clinically meaningful easing of tardive dyskinesia (TD) — the repetitive and jerky movements caused by antipsychotics – and to high levels of patient satisfaction, data from a Phase 3 clinical trial of Neurocrine Biosciences’ treatment show. The results, “Effects of Long-Term Valbenazine on…

The Parkinson’s Foundation announced that it investing $6.2 million across 53 research grants, part of its commitment to advancing promising work into the disease. The grants will support Parkinson’s clinical trials and research centers. They also include career development and fellowships for scientists working in multiple aspects of related research. “Our goal at…

Thinning of the eye’s retina appears to be associated with Parkinson’s and, possibly, with disease severity, a study reports, suggesting that an eye scan might be used at some point to detect Parkinson’s in its earliest stages, before motor symptoms begin. The study, “Retinal thinning associates with nigral dopaminergic loss in…

A new online exercise training program for professionals working with Parkinson’s disease patients has been launched by the Brian Grant Foundation (BGF). This free program is geared toward physical therapists, personal trainers, and group fitness instructors to assist them in developing safe and effective training classes for those…

Tiny bleeds in the brain are associated with cognitive impairment in Parkinson’s disease and risk of Parkinson’s disease dementia (PDD), a Japanese study has found. The research, “The presence of cerebral microbleeds is associated with cognitive impairment in Parkinson’s disease,” was published in the Journal of…

Low-frequency subthalamic deep brain stimulation (STN-DBS), but not high-frequency STN-DBS, reduces freezing of gait in Parkinson’s patients while preserving their ability to simultaneously process motor and cognitive information, a recent study shows. The study, “Decreasing subthalamic deep brain stimulation frequency reverses cognitive interference during gait initiation in…

Low levels of a specific chaperone  protein might be implicated in the development of Parkinson’s disease and Lewy body dementia, according to new research. The protein may be a promising therapeutic target to treat Parkinson’s, with researchers pursuing this possibility in preclinical studies. The study, “…

Patients diagnosed with Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) were found to have a mortality rate more than three times higher than the general population, according to researchers in Sweden. The 10-year follow-up study, titled “Relative survival in patients with dementia with Lewy bodies…