News

Parkinson’s Disease Biomarkers Are Target of New Research Effort

Researchers at University of California, San Diego School of Medicine, are using a $375,000 grant from the Michael J. Fox Foundation (MJFF) to support work aiming to identify blood biomarkers that might finally lead to an early diagnosis of Parkinson’s disease. “One of the really unmet needs with Parkinson’s disease is the creation…

Parkinson’s Might Be Detected Early Using Visual Profiling

York University researchers have reported a new method of visual profiling that could help in the early detection of Parkinson’s disease. The study, titled “Classification of Parkinson’s Disease Genotypes in Drosophila Using Spatiotemporal Profiling of Vision,” was published in Scientific Reports. Parkinson’s is a disorder that affects motor…

Aspirin Molecule Targets Enzyme Active in Neurodegeneration

Researchers at the Boyce Thompson Institute and Johns Hopkins University have discovered that salicylic acid, the primary product from aspirin breakdown, binds to and blocks an enzyme thought to play a major role in neurodegenerative diseases, including Parkinson’s disease. The research paper, titled “Human GAPDH Is a Target of Aspirin’s Primary…

Parkinson Foundation Helpline Reaches 50,000-Call Milestone

The National Parkinson Foundation (NPF) announced that a proud milestone has been reached: it recently aided the 50,000th caller through its toll-free NPF Helpline. “NPF’s Helpline links our groundbreaking research to improve the lives of people with Parkinson’s today directly with the community we serve,” John Kozyak, the NPF’s Chairman of the…

In Parkinson’s and Like Diseases, Cleansing Proteins Are Disrupted

Researchers have identified a specific protein involved in the functional upkeep of synaptic activity and detailed the process behind optimal neurotransmission — an activity whose breakdown is a defining feature of Parkinson’s and other neurodegenerative diseases. The research paper, entitled “Hsc70-4 Deforms Membranes to Promote Synaptic Protein Turnover by Endosomal Microautophagy” was published…

Exercise in Older Parkinson’s Patients May Lower Risk of Falling

Exercise can be a powerful prescription for improving movement in Parkinson’s disease (PD) patients. Researchers, trying to pinpoint those exercises that might best quell PD symptoms, recently reported that both power training and yoga were helpful to older people with PD. Their study, titled “Comparative Impact of Power Training…

Countering Parkinson’s Treatment-induced Spasms

Scientists have identified a new strategy to attenuate one of the side effects — uncontrolled movement — caused by levodopa, the most effective treatment in the management of Parkinson’s disease symptoms. The study, entitled “M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia,” was published…