News

A protein found in a common liverwort plant could be engineered to clear the toxic protein clumps associated with Parkinson’s disease, according to a new study. Researchers discovered that this plant-based protein acts as a “molecular bridge,” successfully linking harmful alpha-synuclein to a human cell’s internal recycling…

The first patient has been dosed in a U.S. clinical trial testing Iregene Therapeutics’ off-the-shelf, or ready-to-use, cell therapy NouvNeu001 for Parkinson’s disease. The therapy was delivered to both sides of the putamen — a brain region deeply affected in Parkinson’s and central to movement control — in…

Urinary tract infections (UTIs) are common among people hospitalized with Parkinson’s disease and are linked to longer hospital stays and a slightly higher risk of delirium, according to a retrospective analysis of 321,967 Parkinson’s-related hospitalizations from a large U.S. hospital database. The findings…

The Parkinson’s Foundation and the American College of Sports Medicine (ACSM) are teaming up to make exercise more accessible and sustainable for people with Parkinson’s disease — while keeping patients safe. The foundation and the ACSM, which bills itself as the world’s largest sports medicine and exercise science organization,…

A Phase 1b clinical trial evaluating Serina Therapeutics’s SER-252 (POZ-apomorphine) in people with advanced Parkinson’s disease has enrolled its first patient, the company announced. The global registrational trial is evaluating the treatment’s safety, tolerability, pharmacokinetics, and preliminary efficacy. The first group of participants is being enrolled in Australia, where…

The weight loss commonly seen in Parkinson’s disease isn’t just about eating less. It’s about a fundamental shift in how the body fuels itself. According to a new study, Parkinson’s patients primarily lose body fat, not muscle, because their bodies struggle to process glucose, a complex sugar the body…

Six months of regular aerobic exercise can partially “normalize” disrupted brain communication in people with Parkinson’s disease, a new Canadian study suggests. By cycling for an hour three times a week, patients saw shifts in their brain networks that moved in the opposite direction of the disease’s typical pattern, suggesting…

People with Parkinson’s disease have altered levels of certain metals, including iron, in their hair, according to a new study. Experiments in a mouse model suggest these iron changes may be linked to intestinal changes consistent with a reduced capacity to absorb iron, along with increases in gut bacteria genes…

Depression that starts later in life could be an early clinical manifestation of Parkinson’s disease and the related condition dementia with Lewy bodies (DLB), according to a study, which found that people who were diagnosed with either of these conditions had significantly higher rates of incident depression than…

Women with Parkinson’s disease have more uneven and unstable muscle contraction than men, even when their clinical symptoms are similar, a study found. The differences are related to the firing of motor units; a motor unit is a single nerve cell and the muscle fibers it controls, which together…