APOE Variant Directly Tied to Lewy Body Dementias in 2 Studies
A variant of the apolipoprotein (APOE) protein, called APOE4, has been shown to directly affect Lewy body dementias, such as Parkinson’s disease. Two separate studies, published simultaneously, found that APOE4 directly regulates levels of alpha-synuclein, which clumps to form the nerve-damaging Lewy…