Poor quality of sleep is linked to worse motor and nonmotor symptoms in people with Parkinson’s disease, a study has found. Greater deviations from an estimated ideal bedtime, time in bed, and duration of sleep are linked to more severe symptoms, data show. “Sleep disorders have a significant effect…
Certain genetic mutations may help determine the length of survival in Parkinson’s disease patients, according to findings by a team of researchers from four institutes in Paris. Patients with Parkinson’s who carried a mutation in either the LRRK2 or the PRKN genes were found to live longer than those…
The use of antidepressants or anti-anxiety medications was linked to the development of Parkinson’s disease in women 65 and older, a U.S. study found. Using more than one of these medications, or changing medications over time also were significantly tied to a further increased risk, data showed. “Study findings…
To help ensure all Parkinson’s patients have the care and support needed to enhance their life quality, the Parkinson’s Foundation has expanded its Global Care Network — launching new centers in five states that had none. In all, the Parkinson’s Foundation opened four Centers of Excellence and six…
A July 9 event aimed at African Americans will underscore the importance of an early Parkinson’s disease diagnosis and specialized healthcare, while addressing institutional biases and myths that can impede such detection and treatment. The free program, called “Parkinson’s Disease and the African American Community,” will be held in…
Eight weeks of leg strength training failed to prevent sudden drops in blood pressure upon standing, a condition called orthostatic hypotension, in people with Parkinson’s disease, according to a small pilot study. “Further controlled clinical trials with larger sample sizes and sufficient power are required to investigate the effect…
A protein called TMEM175 is critically important for maintaining the proper acidity of lysosomes — cellular compartments that clear waste — and its deficiency led to the buildup of the toxic protein alpha-synuclein in the brains of mice. That finding from a recent study may underlie the previously identified link…
Scientists in Germany have developed the first highly sensitive test to detect altered alpha-synuclein proteins in blood samples from patients with Parkinson’s disease. The test accurately distinguishes people with Parkinson’s from those without the disease and has the potential to detect the disease early, before symptoms start, according to…
Overactivation of microglia cells — known to drive neuroinflammation in diseases like Parkinson’s — can be detected by measuring a panel of different proteins in the cerebrospinal fluid (CSF), the liquid that surrounds the brain and spinal cord, a study reports. The finding supports the potential of these proteins as…
ABBV-951, AbbVie‘s experimental under-the-skin formulation of levodopa/carbidopa, was generally well-tolerated and increased average “on” time by more than three hours among people with Parkinson’s disease. Those results from a Phase 3 open-label clinical trial were shared at the 8th European Academy of Neurology (EAN) Congress in Vienna, Austria, in…
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