News

Gastrointestinal (GI) dysmotility, or lack of movement, can impair the absorption and delay the effects of levodopa-based medication in people with Parkinson’s disease, a study reports. Notably, the study describes the cases of two Parkinson’s patients who stopped responding to levodopa/carbidopa intestinal gel — available under the brand name…

Treatment with an herbal preparation called Tongtian oral liquid, long used in traditional Chinese medicine, helped to prevent nervous system damage and normalize movement in a zebrafish model of Parkinson’s. Scientists in China reported these findings in the study, “Neuroprotective effects of Tongtian oral liquid, a…

A new carbidopa/levodopa oral therapy for Parkinson’s disease, called Dhivy, is now available in the U.S., its manufacturer Avion Pharmaceuticals announced. According to Avion, Dhivy is the first and only such therapy available as a tablet with four snappable segments, allowing for more precise dosing of carbidopa/levodopa. “The…

Metabolomics — global analyses of the many small, biologically relevant molecules in blood — may help to identify males with Parkinson’s disease who carry a mutation in the LRRK2 gene, allowing for earlier diagnosis, a study reported. The study, “Plasma Metabolite Signature Classifies Male LRRK2 Parkinson’s Disease…

Collecting finger tapping, voice, and walking data on a smartphone to be digitally processed by deep machine learning tools can accurately distinguish between people with and without Parkinson’s disease, a study of more than 7,000 people reported. This approach, known integrative digital biomarkers, may help to diagnose the disease…

In the culmination of a woman’s 10-year campaign, the government of Ontario, Canada, has agreed to recognize Parkinson’s disease (PD) as an occupational disorder linked to the use of McIntyre powder, an aluminum-based inhalant, in mining and other industries. The decision by Ontario’s Workplace Safety and Insurance Board (WSIB) was…

Loss of a protein called DJ-1, which is linked to the development of early-onset Parkinson’s disease, may also mean a longer-lasting immune response, according to a new study. Researchers observed that immunoaging — a decline in immune function with aging — was slowed in a man with Parkinson’s who…

Mice in a Parkinson’s disease model treated at higher doses with the anti-anxiety medication buspirone had lesser evidence of nerve cell degeneration in the brain and more normalized behaviors than untreated mice, a pair of researchers in Australia reported. “To our knowledge, this is the first study to investigate the ability…

Winners of the 2022 edition of the $3 million Cure One, Cure Many Award for the early diagnosis of Lewy body dementia (LBD) have been announced by its promoter, the American Brain Foundation. They are the Mayo Clinic’s Owen A. Ross, PhD, Pamela J. McLean, PhD, and…

Older age at disease onset among people with Parkinson’s is associated with a more rapid increase in the severity of motor symptoms, as well as a faster decline in health-related quality of life, a new study found. According to investigators, understanding the factors underlying the development of symptoms “is…