Treatment with the low-dose painkiller ketamine eased levodopa-induced dyskinesia (uncontrollable body movements) in patients with Parkinson’s disease, according to results from a Phase 2 study sponsored by PharmaTher. The trial (NCT04912115) evaluated how well a low dose of ketamine that does not induce anesthesia works to reduce levodopa-induced…
Based on survey results indicating that pandemic restrictions considerably aggravated Parkinson’s disease (PD) symptoms and hampered care, Parkinson’s UK is calling on its various governments to take remedial steps to improve both care and access. Calls for action derive from a 41-page report by the nonprofit organization and Lancaster…
Treatment with oral IPX-203, Amneal Pharmaceuticals’ investigational extended-release carbidopa-levodopa (CD/LD) formulation, reduced “off” time by about 1.5 hours a dose, on average, compared to immediate-release tablets of the medication, according to data from a Phase 3 RISE-PD clinical trial. Top-line results from RISE-PD were announced last year. Detailed…
To celebrate Parkinson’s Awareness Month, this year’s INSIGHT into Parkinson’s meeting will be the longest World Parkinson’s Day conference to date and focus on research updates and practical suggestions to improve the lives of people with Parkinson’s disease. World Parkinson’s Day takes place on April 11, and April…
Signs of frozen gait are most noticeable when people with Parkinson’s disease are turning or walking in a circle, and more noticeable when they are walking backward rather than forward, a small study reported. Three distinct characteristics of walking — step length, walking speed, and range of joint motion —…
A surgery-like brain procedure called gamma knife thalamotomy may help to ease tremor in people with Parkinson’s disease, a new study highlights. The study, “Gamma Knife stereotactic radiosurgery as a treatment for essential and parkinsonian tremor: long-term experience,” was published in Neurología. Tremor is one of…
A gene called Fer2 in fruit flies is essential for maintaining the health of dopamine-producing nerve cells and does so by supporting the cells’ mitochondria, which provide them with energy, a study reports. The human equivalent of this gene — a mammalian equivalent, called Nato3, was identified in mice — may…
SQZ Biotechnologies has received a $2 million grant to work out a way to turn a patient’s own immune cells into nerve cells (neurons) capable of producing dopamine, offering a new approach to treat Parkinson’s disease. Valid for two years, the Phase II grant for Small Business Innovation…
Parkinson’s News Today is bringing back its “30 Days of Parkinson’s” initiative for the second year during Parkinson’s Disease Awareness Month in April. This project is aimed at raising awareness by highlighting different voices within the Parkinson’s community. Every day in April, we will feature a story from someone…
A real-time, home-monitoring system allowed for remote detection and management of orthostatic hypotension — a sudden drop in blood pressure when changing positions — in people with Parkinson’s disease during the COVID-19 pandemic, a pilot study shows. Notably, the eight patients involved reported these episodes profoundly affect daily life…
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