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January 20, 2020January 20, 2020

International Group Reflects on Decade Of Collaborative Parkinson’s Genetics Research, Notes Future Plans

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A decade after its founding, the International Parkinson Disease Genomics Consortium (IPDGC) is looking back on on its first 10 years of research and outlining its goals for the ... Read more

January 20, 2020January 20, 2020

Deleting Specific Region of Alpha-Synuclein Protein May Prevent Parkinson’s Symptoms, Fly Study Suggests

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By deleting a section of alpha-synuclein, a protein that forms damaging clumps in the brains of Parkinson’s disease patients, researchers were able to prevent Parkinson’s-like symptoms in fruit flies, ... Read more

January 17, 2020January 17, 2020

Case Report Describes Secondary Parkinsonism Due to Cavernoma in the Striatum

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Secondary parkinsonism can be caused by a cavernoma — a cluster of abnormal blood vessels — located in a brain region involved in voluntary movement control, a case report ... Read more

January 17, 2020January 17, 2020

Gut Bacteria Protects Against Alpha-Synuclein Buildup in Nerve Cells in Worm Model, Study Shows

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A common gut bacteria called Bacilus subtilis (B. subtilis), which aids in digestion, shows the potential to counteract the misfolded alpha-synuclein protein central to Parkinson’s disease, according to a ... Read more

January 16, 2020January 16, 2020

Cerevel Therapeutics Initiates Phase 3 Program Testing Tavapadon for Improved Motor Function

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Cerevel Therapeutics announced its launch of a series of Phase 3 clinical trials to evaluate its investigational therapy tavapadon, designed to improve motor function in people with Parkinson’s disease. ... Read more

January 16, 2020January 17, 2020

Potential Oral Treatment Shows Promise in Early Study in Volunteers, Neuropore Says

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A potential oral therapy for Parkinson’s disease and amyotrophic lateral sclerosis (ALS) was seen to be safe and well-tolerated at various doses in a Phase 1 trial in healthy volunteers, ... Read more

January 15, 2020January 15, 2020

Project Aiming to Create Working Neurons Awarded $4M Grant

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A team of researchers at Purdue University won a $4 million grant from the National Science Foundation to advance the development of a synthetic neuron platform to support future ... Read more

January 15, 2020January 15, 2020

Biogen Acquires Pfizer’s PF-05251749, a Potential Disease-modifying Therapy for Parkinson’s, Alzheimer’s

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Biogen is adding Pfizer’s PF-05251749 — a regulator of the body’s inner clock — to its group of potential disease-modifying therapies for Parkinson’s and Alzheimer’s diseases. Biogen plans to test ... Read more

January 14, 2020January 14, 2020

Affiris Announces Phase 2 Study of Potential Parkinson’s Vaccine

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Affiris is preparing for a Phase 2 clinical trial to test Affitope (PD01A), an experimental medicine that, if successful, could lead to a vaccine against Parkinson’s disease. Affitope triggers the ... Read more

January 14, 2020January 14, 2020

One-year Results in 2 Given Gene Therapy at Low Dose Showing Promise, Axovant Reports

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Two Parkinson’s patients treated with AXO-Lenti-PD, an investigative gene therapy, in an ongoing clinical trial continue to show improvement 12 months later, Axovant, the therapy’s developer, said in a release. ... Read more

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