News

Satisfaction and Interest Strong for Remote Trials, Study Finds

People who took part in remote, video-conducted clinical trials for Parkinson’s disease reported high levels of satisfaction and interest in participating in future studies with remote video visits, scientists report. Three such trials showed that recruitment was feasible and enrolled participants were geographically dispersed — from across dozens of…

Psychosis Common With Late-stage Parkinson’s, Study Reports

Psychosis, including hallucinations and delusions, is frequent in people with late-stage Parkinson’s disease a study reported, after psychotic symptoms were confirmed in more than half of the 92 patients examined. Some degree of cognitive impairment was found in almost all evaluated patients, with study participants diagnosed a mean of 15.9…

Speech Problems in Patients May Indicate Freezing of Gait Risk

Speech impairments appear to associate with freezing of gait symptoms — a sudden inability to walk — in people with Parkinson’s disease, a study reported. Speech assessments, especially during the “on-state” of medication use — immediately after taking dopamine-based medicines — may identify Parkinson’s patients vulnerable to freezing of…

Companies Using AI to Identify Small Molecules to Treat Parkinson’s

Iktos is working with Astrogen to use artificial intelligence (AI) to identify small molecules as candidates for the treatment of Parkinson’s disease. Under the collaboration’s terms, Iktos will apply its proprietary machine-learning algorithm to virtually “sketch”molecules directed against a defined target and shortlist candidates for preclinical studies, the companies…

FDA Awards Final Approval to Entacapone Generic for Wearing-off

Alembic Pharmaceuticals has received final approval from the U.S. Food and Drug Administration (FDA) for its generic version of entacapone as an add-on therapy for treating end-of-dose “wearing off” in Parkinson’s disease, the company announced. These entacapone tablets are “therapeutically equivalent” to Comtan and treat the motor…

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