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March 22, 2019March 22, 2019

Grant Will Enable Pharmacologist to Expand Gaucher Disease Research to Parkinson’s

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As it sometimes happens in rare-disease research, a prospective therapy for one disorder has potential to help another. So it is that, at Temple University, molecular pharmacologist Marlene Jacobson, PhD, ... Read more

March 22, 2019March 22, 2019

Motor Dysfunction Among the Predictive Markers of Parkinson’s for People with Sleep Disorder, Study Reports

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Mild cognitive impairment, motor and olfactory deficits, and erectile dysfunction are among the markers able to predict the development of Parkinson’s and associated disorders in people with rapid eye ... Read more

March 21, 2019March 21, 2019

ProMIS to Present Data on Potential of Antibodies to Target Toxic Alpha-Synuclein in Parkinson’s

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ProMIS Neurosciences will present evidence of the selectivity of several of its antibody candidates to target the toxic forms of alpha-synuclein, a key component of Lewy bodies that underlie the development of Parkinson’s disease. ... Read more

March 21, 2019March 22, 2019

Hydrotherapy Improves Balance, Mobility in Parkinson’s Patients, Study Reports

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Hydrotherapy may provide significant balance and mobility benefits in patients with Parkinson’s disease compared to medication and land-based exercises, according to a review study. The research, “The Effects of Hydrotherapy ... Read more

March 20, 2019March 22, 2019

Trunk Exercises May Improve Balance in Parkinson’s Disease, Study Finds

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Exercise and fall prevention education can improve front-to-back trunk mobility in Parkinson’s patients with a history of falls, according to a Phase 2 clinical trial. The study, “Trunk exercises ... Read more

March 20, 2019March 20, 2019

Alpha-Synuclein Impairs ClpP Enzyme, Causing Mitochondrial Damage, Study Says

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Alpha-synuclein reduces the levels and impairs the function of ATP-dependent Clp protease (ClpP), an enzyme found in mitochondria — the cell compartments responsible for the production of energy — causing mitochondrial ... Read more

March 19, 2019March 22, 2019

Proper Nutrition May Prevent More Severe Motor Problems in Parkinson’s, Study Suggests

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Maintaining good nutritional status may protect Parkinson’s patients from greater motor impairments associated with weight loss, according to new research. The study, “Untangling the relationship between fat distribution, nutritional ... Read more

March 19, 2019March 19, 2019

Parkinson’s Patients with Poorer Quality of Life May Benefit the Most from Deep Brain Stimulation, Study Finds

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Individuals with Parkinon’s disease who have worse quality of life due to their disease-related impairments may benefit most from treatment with deep-brain stimulation. The study with that finding, “Quality ... Read more

March 18, 2019March 19, 2019

Deep-brain Stimulation Can Reverse Mitochondria Defects Linked to PD, Study Finds

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Deep brain stimulation therapy can help lessen Parkinson’s symptoms, partly by increasing the number of mitochondria — cells’ powerhouses — in brain nerve cells, a study shows. The study, “Post ... Read more

March 18, 2019March 19, 2019

Manganese Exposure May Be Linked to Parkinson’s Development, Study Suggests

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Exposure to the metal manganese may lead to the development of Parkinson’s disease by promoting the release from nerve cells of alpha-synuclein, the subsequent aggregation of which causes inflammation ... Read more

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