Author Archives: Steve Bryson PhD

Some Parkinson’s Medicines May Hurt Levodopa Effectiveness

The use of several Parkinson’s disease medications was significantly associated with the increased abundance of a bacterial enzyme that converts levodopa to dopamine in the gut, potentially reducing levodopa’s availability in the brain, a study found. In Parkinson’s patients with rapidly progressing disease, the approved therapy Comtan (entacapone)…

No Link Found Between Drinking Well Water, Parkinson’s Risk

No significant correlation was found between the consumption of well water and the risk of developing Parkinson’s disease, according to the results of a pooled analysis of multiple studies. However, there was a high degree of variability — what scientists call heterogeneity — between the selected studies, with some…

Lifestyle Factors, Medical Problems May Impact Early-stage Cognition

Lifestyle factors and co-existing medical conditions influence cognition in people in the early stages of Parkinson’s disease, with physical exercise and cognitive stimulation shown to have a protective effect, a large study revealed. High blood pressure, diabetes, and psychiatric problems were found to have a negative impact on cognitive…

Head Tremors Linked to Parkinson’s Severity in Small Study

Greater head motions due to Parkinson’s-related tremors were found to be associated with worse disease severity, a small study in patients reported. As an added diagnostic test in the clinic, measuring the degree of tremors affecting the head may also help in recognizing Parkinson’s early in people, its researchers…

Web-Based Speech Tool May Help ID Parkinson’s in Real World

A new tool that analyzes speech using real-world, web-based recordings — participants are recorded via a webcam and a microphone connected to a personal computer or laptop — identified Parkinson’s disease patients with 74% accuracy, a study demonstrated. Moreover, this speech tool — called Parkinson’s Analysis with Remote Kinetic-tasks,…

Study Finds No Differences in Cognitive Abilities Between Sexes

No differences in cognitive abilities were identified between men and women with Parkinson’s disease, according to a recent study. Although no tests were conducted, the researchers suggested the lack of cognitive differences between male and female patients, which is found in aging healthy individuals, may be due to the…

Extended Dosing Improves Safety of IkT-148009, Animal Studies Show

The safety profile of IkT-148009, an investigational oral medication for Parkinson’s disease, improved the longer the drug was dosed, demonstrating target selectivity, according to interim three-month animal data. The ongoing toxicology studies, conducted by the therapy’s developer, Inhibikase Therapeutics, were designed to meet regulatory requirements for regular…

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