The Michael J. Fox Foundation (MJFF) has named Brit Mollenhauer, MD, a foundation scientific advisor, as the winner of this year’s J. William Langston Award in recognition of her contributions to Parkinson’s research in expanding avenues to new treatments. Mollenhauer’s work has focused on developing…

Regular and sustained physical activity, including daily pursuits such as walking or gardening, may help slow the progression of Parkinson’s in people with early-stage disease, a long-term follow-up study suggests. Patients who exercised regularly over five years showed better motor and cognitive outcomes. “Our results are exciting, because they suggest it…

The Parkinson’s Progression Markers Initiative (PPMI) is expanding to enroll up to 100,000 people with and without Parkinson’s disease through an online portal. This expanded PPMI study (NCT04477785) is particularly seeking to enroll people who were diagnosed with Parkinson’s in the past two years and are not…

Several microRNAs in the blood of people with Parkinson’s disease differ from healthy controls, correlate with disease progression, and are associated with hallmarks of the disorder, a large-scale study reported. These findings support the possible use of microRNAs as biomarkers in…

The Parkinson’s Progression Markers Initiative (PPMI), a study sponsored by The Michael J. Fox Foundation, is recruiting people with known disease risk factors but no official Parkinson’s diagnosis, the foundation announced. Newly diagnosed patients, and healthy adults — those without any known Parkinson’s risk factors, who would…

The Parkinson’s Progression Markers Initiative (PPMI), a study sponsored by The Michael J. Fox Foundation, is expanding to recruit more participants, the Foundation announced. Currently, the study (NCT04477785) is recruiting new participants — both with and without Parkinson’s disease — at Banner Research Institute in…

Starting treatment earlier does not appear to worsen the course of Parkinson’s disease or be associated with more severe treatment side effects, an observational study reports. The study, “Estimating the Effect of Early Treatment Initiation in Parkinson’s Disease Using Observational Data,” was published in the journal…

Roche presented initial data from an ongoing Phase 2 clinical trial evaluating prasinezumab (PRX002/RG7935) — an antibody against the alpha-synuclein protein — in more than 300 people with early stage Parkinson’s disease. Data highlighted that the trial’s participants, including those on MAO-B inhibitors, represent a wider population…

People with Parkinson’s disease taking part in the Fox Insight study, where they self-report details about their illness, share similar clinical and demographic features with patients brought through more traditional ways into large data studies, researchers report. This finding suggests that groups recruited exclusively online can be useful to Parkinson’s…

Patients with Parkinson’s are at a greater risk of developing impulse control disorders (ICDs) if they are depressed, according to results from an international study. The findings also revealed that treatment with dopamine agonists increases this susceptibility, and caution is advised when prescribing such therapies to depressed Parkinson’s…