Two studies support the safety and tolerability of Nuplazid (pimavanserin) in older or frail adults with psychosis associated with Parkinson’s disease. Safety data on Nuplazid, the only medication approved by the U.S. Food and Drug Administration (FDA) to treat Parkinson’s-associated psychosis, were presented at this year’s International…

Ryan Reynolds is the face of an educational campaign aiming to raise awareness of lesser-known Parkinson’s disease symptoms: the hallucinations and delusions that can be related to the disease. The ‘More to Parkinson’s’ initiative, sponsored by Acadia Pharmaceuticals, features a six-part series in which the actor…

People with Parkinson’s disease who experience digestive issues or probable rapid eye movement (REM) sleep behavior disorder may be as much as twice as likely to develop symptoms of psychosis, a study found. Understanding what predicts early-onset psychosis in Parkinson’s can help doctors identify at-risk patients sooner, enabling them…

Nuplazid (pimavanserin) outperformed a placebo at managing psychosis in people with Parkinson’s disease dementia in a Phase 3 clinical trial. This finding “supports the maintenance of antipsychotic efficacy and safety of [Nuplazid] in patients with Parkinson’s disease dementia and psychosis,” the researchers wrote. Their study, “…

Among several atypical antipsychotics, Nuplazid (pimavanserin) seems to be the most effective at easing Parkinson’s disease psychosis (PDP) while sparing motor function, according to a review study. Clozapine, used off-label in people with Parkinson’s, also helped, but its effect was not as large and patients were more…

Different types of hallucinations — hearing voices, feeling a touch, and detecting smells or tastes, among others — affect a large proportion of people with Parkinson’s disease and have substantial clinical importance, according to a new review study. While visual hallucinations are a known nonmotor symptom of the neurodegenerative…

Mortality rates appear to be lower among people with Parkinson’s disease psychosis (PDP) being treated with Nuplazid (pimavanserin) relative to those using other antipsychotic medications, according to a real-world study in the U.S. The study, “Mortality in Patients with Parkinson’s Disease-Related Psychosis Treated with Pimavanserin…

Most people associate Parkinson’s disease (PD) with shaking, tremors, balance, and gait issues. However, we don’t often consider the impact of PD on vision. According to the American Parkinson Disease Association (APDA), vision issues may cause a number of symptoms. Not every person with PD experiences these issues, but…

The U.S. Food and Drug Administration (FDA) has approved an update to the prescribing information for Nuplazid (pimavanserin) that will allow the medication to be taken more easily by Parkinson’s patients who have difficulty swallowing. Nuplazid, by Acadia Pharmaceutical, is an oral medication that was approved…

PointClickCare has developed a new software tool to aid in the early diagnosis of Parkinson’s disease psychosis. The tool, developed in partnership with the American Society of Consultant Pharmacists (ASCP), is programmed to ask patients a series of questions regarding hallucinations and/or delusions. Based on the responses, senior care…