In people with early-stage Parkinson’s disease who had yet to be treated, high levels of the proteins tau and P-tau181 in the cerebrospinal fluid, or CSF — the fluid surrounding the brain and spinal cord — predicted faster motor and cognitive decline, per a new study with eight years…
Weekly dance classes may help attenuate symptoms of depression in people with Parkinson’s disease, which results in changes in the brain toward better emotional control, a study from York University in Toronto suggests. “We’re not trying to cure Parkinson’s with dance,” Joseph DeSouza, PhD, who led the study, said…
In 2024, Parkinson’s News Today kept readers informed with updates on the latest research, treatments, and clinical trials for Parkinson’s disease. Here are the 10 most-read stories in 2024, each with a short summary. We look forward to continuing to support the Parkinson’s community and sharing informative stories…
Scientists have developed a nanoparticle drug delivery system designed to enhance brain delivery of levodopa, the mainstay treatment for Parkinson’s disease, while also lowering a type of cellular damage called oxidative stress that’s implicated in the neurodegenerative condition. The system was able to improve motor function in a…
The use of deep brain stimulation — in which an electrode is surgically implanted in the brain — may hold promise to reverse inflammation, a key driver of Parkinson’s disease progression, according to a new study led by researchers in Germany. “Deep brain stimulation halts inflammatory changes in Parkinson’s…
Data from a brief gait and posture assessment using wearable sensors — taking just a few minutes in the clinic — could help to accurately predict the risk of falls in the near future with Parkinson’s disease, a recent clinical study reported. Scientists at the University of Oxford in…
Taking steps to increase patient education about osteoporosis — a bone-weakening condition that’s common in people with Parkinson’s disease — could potentially lower the risk of falls and encourage higher calcium intake for stronger bones among those with both conditions, a new study suggests. The researchers recommended distributing an…
Treatment with investigational antibody therapy prasinezumab tended to slow the progression of motor symptoms in people with early-stage Parkinson’s disease in a Phase 2b trial, with particularly pronounced benefits among those also receiving levodopa. However, the difference between prasinezumab and a placebo in the overall study population…
Tracking how the brain responds to different emotions may be an effective way to detect Parkinson’s disease, a new study posits. The study, “Exploring Electroencephalography-Based Affective Analysis and Detection of Parkinson’s Disease,” was published in Intelligent Computing. Along with its characteristic motor symptoms, Parkinson’s can…
Adaptive deep brain stimulation (aDBS) resulted in long-lasting relief from bradykinesia and walking difficulties in a 61-year-old Parkinson’s disease patient, whose quality of life also improved, researchers wrote in a case report about the man. Unlike conventional DBS (cDBS), where electric brain stimulation is constant or adjusted manually…
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