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Free APDA conference for patients, caregivers slated for February

The American Parkinson Disease Association (APDA) has announced that it will host its third annual, free, virtual conference for people with Parkinson’s disease and their caregivers on Feb. 19-20. The program is scheduled to run from 12 p.m. to 4 p.m. ET each day. Tailored to “educate, empower…

Vyalev helped man sleep better at night, move during day: Report

Treatment with Vyalev (foscarbidopa and foslevodopa) eased motor symptoms and sleep disturbances in a 50-year-old man with Parkinson’s disease and a history of dream enactment behavior, according to a case report from Japan. Dream enactment behavior is a sign of rapid eye movement (REM) sleep disorder, in which…

New tool could show how genetic variants raise Parkinson’s risk

A new screening method may shed light on the interactions between genetic variants that increase the risk of Parkinson’s disease, providing potential avenues for improving risk prediction and personalized care, a study found. The tool, Variant-variant Interaction through Variable Thresholds (VARI3), is designed to detect and interpret how genetic…

Study unveils mechanisms behind levodopa-induced dyskinesia

The motor cortex, a brain region responsible for movement control, becomes disconnected in levodopa-induced dyskinesia (LID), the uncontrolled movements that occur as a side effect of the drug levodopa in Parkinson’s disease, a study found. Ketamine, an anesthetic used to alleviate LID, was found to restore the motor cortex’s…

Blood pressure treatment eases Parkinson’s tremor in small trial

Propranolol, a blood pressure medication, significantly eased tremor in people with Parkinson’s disease, either at rest or during induced stress, according to findings in a small, placebo-controlled clinical trial. The treatment also significantly attenuated tremor-related brain activity, as indicated on MRI scans. “In about forty percent of patients, […

As temperatures rise, risks climb for people with Parkinson’s

People with neurodegenerative diseases like Parkinson’s disease or dementia are more vulnerable to heat-related complications than those without these conditions, according to a commentary by two neurologists. Medical providers should be trained to understand how heat waves can affect these people, the viewpoint advised. It was co-written by Indu…

Women may need emotional support on road to DBS: US study

Men and women with Parkinson’s disease approach the decision to undergo deep brain stimulation (DBS) distinctively, according to a new U.S. study whose findings are now being used to develop support tools for patients in choosing or not choosing to have the surgery. For example, the study found that…

Aerobic exercise may help Parkinson’s patients after DBS

Aerobic exercise may help relieve non-motor symptoms of Parkinson’s disease in people who have undergone deep brain stimulation (DBS), a small study suggested. The researchers said there’s a need for more studies on exercise and Parkinson’s patients who have had DBS, a surgical treatment that involves implanting an electrode…