Treatment with AB-1005 (AAV2-GDNF), AskBio’s investigational gene therapy, was safe and well tolerated among patients with mild to moderate Parkinson’s disease, according to top-line results from a Phase 1b clinical trial. The company, wholly owned by Bayer, has also completed an 18-month data collection which demonstrated the…
A three-month exercise program focusing on Brazilian dance led to greater gains in lower limb strength among Parkinson’s disease patients than Nordic walking or deep-water exercise programs, according to a clinical trial report. Most measures of motor performance, cognitive function, and quality of life were unaltered by any of…
A growing need for local doctors able to compassionately, as well as accurately, diagnose Parkinson’s disease exists, as the number of people being given a Parkinson’s diagnosis is rising in the U.S. while access to movement disorder specialists — trained in knowing how best to deliver such news…
Richard Wyse, MD, director of clinical development at Cure Parkinson’s, is among those in the United Kingdom (U.K.) recognized for their services to the public through inclusion on His Majesty The King’s New Year’s Honours List. Wyse, recognized for his work with Parkinson’s disease, is among…
Exposure to nanoplastics, micro-sized fragments of plastic waste found in the environment, mimicked the signs and symptoms of Parkinson’s disease in tiny worms and in human nerve cells in the lab, a study reported. Low concentrations of nanoplastics were found to penetrate the walls of the worms’ intestines and…
Using IPX203, an extended-release formulation of carbidopa/levodopa (CD/LD), was associated with a sustained control of symptoms for Parkinson’s disease patients who participated in the open-label extension of the RISE-PD Phase 3 trial. Final results from the nine-month extension study (NCT03877510) indicate dose adjustments and side effects were…
A team led by scientists in the Netherlands is proposing a new screening strategy to test whether pesticides or other chemicals might increase the risk of Parkinson’s disease. “We are still largely in the dark about the safety of these substances. The current admission criteria for pesticides provide insufficient…
Throughout 2023, we at Parkinson’s News Today brought you coverage of the latest scientific advances and developments in treatments for Parkinson’s disease. Here we’ve compiled a list of the top 10 most-read stories published this past year. We look forward to continuing to share more developments with you in…
American football players at the professional level may be more likely to have symptoms similar to those seen in Parkinson’s disease, but the association remains inconclusive, a new study reports. The study, “Examination of parkinsonism in former elite American football players,” was published in Parkinsonism and Related…
More than three-quarters of people with early-onset Parkinson’s disease (EOPD) experience pain, according to a recent study conducted in Vietnam, with more severe pain reported by older patients and those with nonmotor symptoms such as depression, sexual dysfunction, and hallucinations. Additional studies with well-validated tools are needed to further…
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