News

$5M NIH grant will advance study of how brain regulates movement

A five-year project funded by a $5 million National Institutes of Health (NIH) research grant will study how the brain regulates movements, by allowing people with Parkinson’s disease to play video games during brain surgeries. The goal, according to researchers, is to obtain information that can be applied to…

IRLAB ramps up for mesdopetam Phase 3 program in Parkinson’s

IRLAB Therapeutics is taking steps in preparation for a Phase 3 clinical program of mesdopetam, an experimental medicine for the treatment of levodopa-induced dyskinesia in Parkinson’s disease. The Swedish company is consulting with two advisors, Clintrex and ProPharma Group, to gather the documentation needed to request…

3D brain model will be used in pursuit of therapies

Stem Pharm and Verge Genomics are teaming up to develop a 3D brain model of Parkinson’s disease that uses advanced computational tools to validate new therapeutic candidates. The collaboration will leverage Stem Pharm’s human-derived “mini-brains” that model inflammation of the brain — neuroimmune organoids — and Verge’s…

Parkinson’s Foundation names a comprehensive care center in Ohio

In recognition of the high level of specialized care it provides to Parkinson’s disease patients, the Ohio State University Wexner Medical Center has been named a Parkinson’s Foundation Comprehensive Care Center, the only hospital center in Ohio with that designation. “The Parkinson’s Foundation Comprehensive Care Center designation symbolizes…

FDA asked again to approve apomorphine pump SPN-830

Supernus Pharmaceuticals has asked the U.S. Food and Drug Administration (FDA) again to approve the apomorphine infusion pump SPN-830 for treating Parkinson’s disease. “We look forward to continuing our effort with the FDA throughout the NDA [new drug application] review process to bring a promising alternative to…

Toxic alpha-synuclein protein seen to alter energy use in nerve cells

Toxic clumps of the protein alpha-synuclein change the way the brain cells most affected by Parkinson’s disease utilize energy, a study shows. Its researchers wanted a clearer understanding of how “key metabolic processes” are affected by the protein’s aggregation, damaging “vulnerable” nerve cells within the brain, they wrote. To…