Six genetic variants associated with mortality and motor progression have been discovered in people with Parkinson’s disease. These newly detected genetic factors that influenced disease progression were largely different from those that increased Parkinson’s risk, researchers found. “This work will help us to better understand the biology of [Parkinson’s]…
For the first time, two table tennis players with Parkinson’s disease will represent the nonprofit ITTF Foundation at the ITFF World Masters Championships Rome 2024. The players, Steve Morley and Agnes Jan, will join a record field of more than 6,000 athletes at the July 6-14 event at…
Early preliminary data from a pilot study by Stimvia shows a noninvasive neuromodulation device known as URIS eased symptoms among participants in a pilot clinical trial and may serve as an add-on treatment for Parkinson’s disease. The device’s developer plans to release the complete data in the coming months. “We…
Gut microbes may play an important role in driving the low-grade inflammation that naturally occurs with aging and is exacerbated in conditions like Parkinson’s disease, according to research in mice. Older mice were found to have a distinct immune signature reflective of inflammation in the gastrointestinal tract that was…
Preventing the growth of gut bacteria that cause levodopa (L-dopa) to be broken down before it reaches the brain could help boost its therapeutic effects in Parkinson’s disease, according to recent preclinical research. A family of molecules called mitochondrial-targeted drugs (MTDs) were found to inhibit the levodopa-metabolizing bacteria Enterococcus…
The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has awarded a $595,000 grant to Alchemab Therapeutics to advance research on the therapeutic effects of an antibody targeting the prostaglandin pathway in people with Parkinson’s disease. The grant comes from the foundation’s Parkinson’s Disease Therapeutics Pipeline Program,…
Spinal cord stimulation (SCS) was able to safely improve postural problems for people with Parkinson’s disease, according to a very small trial in China. Among the six patients who had the procedure, some gains in aspects of motor function were observed, although the findings were variable, but the researchers…
The use of medical cannabis in the U.S. has grown as more states legalize it, and programs listing Parkinson’s disease-related conditions, including muscle cramps, anxiety, and pain, have expanded from 28 states to 36 in just five years. Yet a survey found many doctors are not aware of the…
A group of light-responsive receptors in nerve cells called kalium channelrhodopsins can effectively turn off nerve cells in the brain, offering a potential way for scientists to dissect the mechanisms underlying brain function and what goes awry in diseases like Parkinson’s, a study found. The study, “…
Lactulose — a synthetic (lab-made) sugar used to soften stools — may ease symptoms of constipation in people with Parkinson’s disease, lowering a need for rescue laxatives, a pilot study found. While these findings come from a small number of patients, they offer grounds for further research into lactulose’s…
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