News

Home-based digital monitoring discerns motor fluctuation profiles

Monitoring symptoms at home using smartwatch-smartphone technology collected individual profiles of tremor and activity fluctuations among people with advanced Parkinson’s disease being treated with levodopa. The technology can provide useful information to improve treatments and patient outcomes and, by combining it with telemedicine and other digital health tools, could…

Afzelin, a plant compound, shows neuroprotective potential in study

A plant compound called afzelin lessened motor abnormalities in a rat model of Parkinson’s disease, a study reports. Afzelin, found in certain plants like some water lilies and trees, has been shown to have a variety of pharmacological properties, including antioxidant and anti-inflammatory effects, that might benefit people with…

Gene therapy AB-1005 found safe in Phase 1b Parkinson’s trial

Treatment with AB-1005 (AAV2-GDNF), AskBio’s investigational gene therapy, was safe and well tolerated among patients with mild to moderate Parkinson’s disease, according to top-line results from a Phase 1b clinical trial. The company, wholly owned by Bayer, has also completed an 18-month data collection which demonstrated the…

Cure Parkinson’s Richard Wyse honored by King Charles

Richard Wyse, MD, director of clinical development at Cure Parkinson’s, is among those in the United Kingdom (U.K.) recognized for their services to the public through inclusion on His Majesty The King’s New Year’s Honours List. Wyse, recognized for his work with Parkinson’s disease, is among…

IPX203 shows sustained safety, efficacy in RISE-PD extension trial

Using IPX203, an extended-release formulation of carbidopa/levodopa (CD/LD), was associated with a sustained control of symptoms for Parkinson’s disease patients who participated in the open-label extension of the RISE-PD Phase 3 trial. Final results from the nine-month extension study (NCT03877510) indicate dose adjustments and side effects were…

Top 10 Parkinson’s stories of 2023

Throughout 2023, we at Parkinson’s News Today brought you coverage of the latest scientific advances and developments in treatments for Parkinson’s disease. Here we’ve compiled a list of the top 10 most-read stories published this past year. We look forward to continuing to share more developments with you in…