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People diagnosed with attention deficit/hyperactivity disorder (ADHD), usually detected at an early age in hyperactive children, may have an increased risk of developing Parkinson’s and Parkinson’s-like diseases, a new study suggests. “Parkinson’s disease is commonly thought of as a neurodegenerative disease associated with aging,” Glen Hanson, PhD, professor at the…

Using a new screening strategy, researchers have identified compounds that block the clumping of alpha-synuclein protein, a key event in Parkinson’s. The study, “Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State,” appeared in the journal Cell Chemical Biology. Aggregated alpha-synuclein is…

Hoping to lure new researchers to the Parkinson’s disease field and to support others’ new and innovative ideas, the American Parkinson Disease Association (APDA) has awarded more than $1.7 million in fellowships, research grants, and funding for APDA Centers for Advanced Research.  The awards include a highly…

The anti-inflammatory molecule interleukin (IL)-4 contributes to the neurodegeneration observed in Parkinson’s disease, a study in rats reports. The research, “Interleukin-4 Contributes to Degeneration of Dopamine Neurons in the Lipopolysaccharide-treated Substantia Nigra in vivo,” was published in the journal Experimental Neurobiology. Parkinson’s is characterized by the progressive…