The impact of climate change and environmental risk factors on brain health was spotlighted at this year’s World Congress of Neurology, a gathering of scientists and clinicians to discuss the latest advances and future developments in neurology. The recent XXIV World Congress of Neurology in Dubai, United Arab Emirates,…
News
Researchers have developed algorithms that work with wearable sensors to continuously monitor tremor, and estimate total tremor, in Parkinson’s patients as they go about their daily routines. Analyses of sensor results using one algorithm, in particular, were similar to an established test assessing tremor without being dependent on the time the…
A particular signaling protein in the brain, called melanin-concentrating hormone (MCH), was seen to help regulate impulse control in rats, a study reports. This finding may have implications for disorders where impulse behaviors manifest, from binge eating and drug addiction to Parkinson’s disease. The study, “Hypothalamus-hippocampus circuitry…
The U.S. Defense Department has awarded researchers from Northeast Ohio Medical University (NOMU) and Michigan State University (MSU) about $1 million each to study the effect of exercise at different stages of Parkinson’s disease. The three-year grant went to longtime collaborators Sheila Fleming, PhD,…
News
LRRK2 Inhibitors May Benefit Parkinson’s Patients With and Without Genetic Mutation, Study Finds
Inhibiting the activity of LRRK2 kinase — an enzyme whose mutated form is one of the most common genetic causes of Parkinson’s disease — may benefit patients both with and without this disease-related mutation, a study finds. Molecules that block the activity of the LRRK2 kinase —…
The way the brain of a Parkinson’s disease patient is wired may help doctors predict if he or she will develop impulse control disorders following dopamine replacement therapy, a study finds. The results, “The structural connectivity of discrete networks underlies impulsivity and gambling in Parkinson’s disease,”…
Both power and strength training can improve muscle performance in people with Parkinson’s disease, but these improvements may not translate to functional movement, a new study has found. The study, titled “Power vs strength training to improve muscular strength, power, balance and functional movement in individuals diagnosed…
Fesoterodine fumarate, the active compound of a medication for overactive bladder, can help reduce urinary symptoms in Parkinson’s disease patients, a clinical study has found. The findings, “Randomized, controlled trial of fesoterodine fumarate for overactive bladder in Parkinson’s disease” were published in the World Journal of…
Treatment with Aricept (donepezil) for six weeks does not seem to improve balance, either while standing or walking, for Parkinson’s patients with a minimal history of falls, according to results from a single-site Phase 2 trial. The study, “Effects of augmenting cholinergic neurotransmission on balance in Parkinson’s…
News
Potential Therapy for Dopaminergic Neurons, CNM-Au8, Enter Phase 2 Trial in Parkinson’s Patients
CNM-Au8, an investigational therapy by Clene Nanomedicine, improved the survival of dopaminergic neurons, helped prevent loss of mitochondria, and rescued motor function in a rat model of Parkinson’s disease, a study reports. The effects of CNM-Au8 will now be assessed in an open-label (no placebo group) Phase 2…
Recent Posts
- Living with Parkinson’s has given me a new perspective on rivalry
- Unixell’s off-the-shelf stem cell therapy cleared for US clinical trials
- Adaptive brain stimulation responds in real time to reduce Parkinson’s falls
- Being reminded that my uncle was still in the room was an important lesson
- MJFF grant funds expansion of trial testing NEU-411 in Parkinson’s