News

Scientists have found that switching off TET2, a gene that provides instructions to make an enzyme that alters the activity of certain genes, can lower inflammation and neurodegeneration associated with Parkinson’s disease. Authors of a study with those findings suggest that reducing the activity of this master gene…

The diets of people with Parkinson’s disease  mostly match those of the general population, but a large portion consume inadequate levels of vitamin D, vitamin B1, zinc, and iron, a Belgian study based on patient questionnaires and dietary pattern records found. Fewer than 20% of these…

The Michael J. Fox Foundation (MJFF) is supporting six different funding programs for projects related to Parkinson’s disease, with applications now being accepted. The six  Requests for Applications (RFAs) are meant to support work focused on different aspects of Parkinson’s research, from data analysis…

Working-age adults with Parkinson’s disease who received deep brain stimulation (DBS) showed better social and occupational functioning than those who received the best medical therapies alone, a study has found. As such, the authors suggest, DBS could be prescribed to…

The Patient-Centered Outcomes Research Institute (PCORI) has awarded the Parkinson’s Foundation and the University of Rochester Medical Center $1.4 million to establish palliative care as a standard across the foundation’s Center of Excellence Network in the U.S. This initiative,  “Implementing Team-based Outpatient Palliative Care in Parkinson Foundation Centers of Excellence,”…

Estimating the severity of Parkinson’s disease may be possible by remotely measuring and analyzing physical activity as patients’ motor impairment increases, research led by scientists at IBM Research suggests. The method uses an artificial intelligence (AI) algorithm that examines movement data sent from wrist-worn accelerometers. It can be…

The small molecule anle138b has shown “excellent” safety and tolerability profiles in a first study in healthy volunteers, and reached therapeutic dose levels in the blood, according to its developer Modag. These results enabled Modag to secure an additional $1.4 million in funding from the Michael J.

The content of dreams, namely dreams with negative emotions, seems to significantly predict long-term cognitive decline in people with Parkinson’s disease, a recent longitudinal study suggests. The association was independent of factors known to impact dream content and cognitive impairment in these patients, its researchers noted. The…

Certain amino acids — the building blocks of proteins — found in the blood and cerebrospinal fluid may be valuable biomarkers of Parkinson’s disease, according to a review study. The review, “Cerebrospinal and blood levels of amino acids as potential biomarkers for Parkinson’s Disease:…

Researchers have developed a highly sensitive but low-cost method to detect dopamine, which may help in the early diagnosis of several disorders characterized by abnormal dopamine levels such as Parkinson’s disease, a study has found.  For the first time, the new…