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Top 10 Parkinson’s stories of 2024

In 2024, Parkinson’s News Today kept readers informed with updates on the latest research, treatments, and clinical trials for Parkinson’s disease. Here are the 10 most-read stories in 2024, each with a short summary. We look forward to continuing to support the Parkinson’s community and sharing informative stories…

Scientists design nanoparticle drug delivery system for levodopa

Scientists have developed a nanoparticle drug delivery system designed to enhance brain delivery of levodopa, the mainstay treatment for Parkinson’s disease, while also lowering a type of cellular damage called oxidative stress that’s implicated in the neurodegenerative condition. The system was able to improve motor function in a…

Prasinezumab slows motor progression, misses main trial goal

Treatment with investigational antibody therapy prasinezumab tended to slow the progression of motor symptoms in people with early-stage Parkinson’s disease in a Phase 2b trial, with particularly pronounced benefits among those also receiving levodopa. However, the difference between prasinezumab and a placebo in the overall study population…

Analyzing emotional reactions could aid Parkinson’s diagnosis

Tracking how the brain responds to different emotions may be an effective way to detect Parkinson’s disease, a new study posits. The study, “Exploring Electroencephalography-Based Affective Analysis and Detection of Parkinson’s Disease,” was published in Intelligent Computing. Along with its characteristic motor symptoms, Parkinson’s can…

Adaptive DBS consistently eased Parkinson’s symptoms in man, 61

Adaptive deep brain stimulation (aDBS) resulted in long-lasting relief from bradykinesia and walking difficulties in a 61-year-old Parkinson’s disease patient, whose quality of life also improved, researchers wrote in a case report about the man. Unlike conventional DBS (cDBS), where electric brain stimulation is constant or adjusted manually…

Study links brain atrophy to tremor progression in Parkinson’s

In people with Parkinson’s disease, shrinkage in tremor-related brain areas is associated with the progression of motor symptoms, according to a study. In the brain’s gray matter, which contains cell bodies of neurons, this shrinkage, or atrophy, of tremor-related regions and the whole brain over two years was associated…