GPNMB Protein May Be Parkinson’s Biomarker, Treatment Target: Study
Levels of a protein called glycoprotein nonmetastatic melanoma protein B (GPNMB) are elevated in the blood of people with…
Articles by Marisa Wexler, MS
Blood-brain Barrier Signaling Found to Help Regulate Nerve Activity
The activity of a molecular signaling pathway called Delta/Notch in cells of the blood-brain barrier is important for regulating the…
Trial Failure of Antibody Targeting Alpha-synuclein Detailed
Treatment with prasinezumab, a monoclonal antibody designed to break up toxic alpha-synuclein aggregates, failed to slow the progression of…
Nanobody Has Potential to Combat Alpha-synuclein Clumps
A miniature antibody-like molecule called a nanobody effectively broke up toxic alpha-synuclein aggregates that are characteristic of Parkinson’s disease,…
Kynmobi Does Not Significantly Alter Heartbeat, Study Finds
Treatment with Kynmobi (apomorphine hydrochloride), an approved under-the-tongue therapy for “off” episodes in Parkinson’s disease, does not substantially…
Project to Develop Self-driving Cars for Parkinson’s Seeks Patients
A new project by scientists at the University of Michigan (UM) aims to design a prototype autonomous vehicle that’s specifically…
Variant in LRRK2, Tied to Disease, Affects Gene’s Activity in Microglia
A Parkinson’s-associated variant in the LRRK2 gene affects the gene’s activity in a single group of brain cells: microglia, the…
Genetic Analysis Links Psoriasis With Faster Disease Progression
Among people with Parkinson’s disease, those with the skin disease psoriasis tend to experience slightly faster disease progression, according…
Aluminum Exposure Boosts Activity of Parkinson’s Genes: Zebrafish Study
Exposure to aluminum increased the activity of several genes related to Parkinson’s disease in zebrafish, a new study shows.
Reduced Bile Acid Levels Seen With Mild Cognitive Impairment
Parkinson’s disease patients who have mild cognitive impairment tend to have lower levels of certain bile acids — substances…