An experimental therapy being developed by Herantis Pharma for Parkinson’s disease was well tolerated and able to penetrate the blood-brain barrier (BBB), a semipermeable membrane that prevents certain substances, including medications, from entering the brain. That’s according to top-line data from a Phase 1b trial (NCT06659562), which…

ARV-102, an oral therapy Arvinas is developing for people with Parkinson’s disease, was shown to reach the brain — where it is needed — and to be safe and well tolerated over two weeks in clinical studies with healthy volunteers and patients. In the volunteers taking part in…

If you are at all familiar with Parkinson’s disease, you’re probably aware of the importance of medication. It’s used for symptom control only, as there is no known cure or disease-modifying therapy for Parkinson’s. Most Parkinson’s symptoms are caused by a lack of dopamine signaling in the brain.

The oral therapy GT-02287, being developed by Gain Therapeutics for people with Parkinson’s disease with or without mutations in the GBA1 gene, was shown to ease motor symptoms and help patients maintain routine daily activities over three months while being safe and well tolerated. That’s according to interim…

When it comes to weird and unexpected symptoms, Parkinson’s disease is the gift that keeps on giving. My grandfather had Parkinson’s, yet when I was diagnosed with it, the only symptom I’d heard of before was tremors. As I eventually learned, that was just the tip of the iceberg.