Among available dopamine agonists to treat early Parkinson’s disease, ropinirole is the least likely to cause dyskinesia, the  involuntary movements that can occur from long-term use of these and other Parkinson’s medications, a meta-analysis study suggests. Pramipexole, meanwhile, may be the least likely to cause wearing off…

I’m back! Not just figuratively, but also literally. I recently took some time off to get my health in check. I was in the process of changing medications, and my neurologist had warned me that I might have side effects or withdrawal symptoms. Boy, was he right. He had been…

An extract from three plant species reduced signs of motor disturbances in rodent models of Parkinson’s disease and lessened the associated molecular defects of the cellular recycling process known as autophagy, a study showed.  Further research is needed to confirm that…

Teva has discontinued Spiroco (ropinirole) 4mg XL prolonged-release tablets due to factors out of the company’s control, according to an announcement from Parkinson’s UK. The company — which outside the U.S. manufactures ropinirole XL as a generic formulation in three concentrations — is still marketing Spiroco…

When used in combination with levodopa, Requip (ropinirole) patches result in greater improvements in motor function compared to placebo for patients with advanced Parkinson’s disease, a Phase 3 clinical trial has found. Trial findings also demonstrated the effectiveness of the new skin patch formulation was not inferior…

Medications used to manage impulse control disorders may not help Parkinson’s disease patients taking Mirapex (pramipexole) and Requip (ropinirole), and may even worsen their episodes, according to new research. The study, titled “What drugs modify the risk of iatrogenic impulse-control disorders…

The first patient has been treated in a clinical trial evaluating Titan Pharmaceuticals’ ropinirole implants, designed to treat the signs and symptoms of Parkinson’s disease. The Phase 1/2 study (NCT03250117) is taking place at three clinical sites in the U.S. that specialize in Parkinson’s research. Researchers…

The U.S. Food and Drug Administration (FDA) has given a green light to Titan Pharmaceuticals to begin a first-in-human clinical trial testing an implant that provides continuous release of ropinirole to treat Parkinson’s signs and symptoms. In the open-label Phase 1/2 trial (NCT03250117), which is now recruiting, roughly 20 Parkinson’s…

Neurologists reported that drugs commonly prescribed for Parkinson’s disease are associated in some people with impulse control disorders such as pathological gambling and binge eating. The article, “Treatment of impulse control disorders in Parkinson’s disease: Practical considerations and future directions,” was published in the journal Expert Review of…