ABBV-951, an under-the-skin formulation of levodopa/carbidopa, outperformed the standard oral therapy at controlling Parkinson’s symptoms in advanced disease patients in a Phase 3 clinical trial, top-line results show. “These data are promising and demonstrate positive results on a key endpoint used to assess efficacy of treatments for patients with…
People with Parkinson’s disease experienced significantly more pain during periods without levodopa therapy, a small study concluded. This finding suggests that the presence, or worsening, of pain could might alert doctors to the need to adjust or review current medication use in this patient population. The study, “…
The nonprofit Parkinson Canada has teamed up with technology company Catalyst to enhance awareness of available digital health tools that can help people with Parkinson’s disease keep up their medication regimen. People diagnosed with Parkinson’s usually require treatment with multiple medications, often with frequent dosing, to adequately…
The U.S. Food and Drug Administration (FDA) has approved Ongentys (opicapone) as an oral, add-on daily treatment for Parkinson’s disease patients experiencing off periods while on a levodopa/carbidopa regimen. The approval is for 25 mg and 50 mg capsules, either taken once a day. It comes after…
Treatment with ADS-5102 (amantadine) significantly decreased levodopa-induced dyskinesia and off-time episodes in patients with Parkinson’s disease at three months, and maintained those benefits for another three months, according to results of a Phase 3 clinical trial that may prove pivotal in the medicine’s approval. Adamas Pharmaceuticals, the treatment’s developer, has filed a New Drug Application…
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