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June 13, 2022 News by Margarida Maia, PhD

‘Off’ Episodes May Affect 1 in 3 Patients Come Bedtime, Trials Find

About 1 in 3 Parkinson’s disease patients in two Phase 3 trials experienced an “off” episode before going to sleep, and most of those who woke up during the night were in an “off” state upon awakening, researchers reported. These findings were pulled from a new analysis of data obtained…

October 8, 2020 News by Marisa Wexler, MS

Ongentys Seen to Shorten Overnight ‘Off’ Periods, Lengthen Good ‘On’ Time

Oral Ongentys (opicapone) as a daily add-on treatment shortened overnight “off” periods and eased dyskinesia during “on” periods in people with Parkinson’s disease using levodopa, new analyses of Phase 3 clinical trial data show. Long-term use was also seen to lower patients’ average daily levodopa dose without worsening symptoms…

October 6, 2020 News by Marisa Wexler, MS

New Data Support Effectiveness of Ongentys for Parkinson’s ‘Off’ Periods

Ongentys (opicapone) can reduce the extent of “off” periods in people with Parkinson’s disease being treated with  levodopa, new clinical trial data show. The data were presented at the American Neurological Association 2020 Virtual Meeting. Therapies that aim to increase levels of dopamine in the brain,…

May 6, 2019 News by Alice Melão

#AANAM – Opicapone Can Prolong ‘On-Time’ Levopoda Provides, Data from Phase 3 Trials Show

Once-daily opicapone can prolong the time during which treatment with levopoda, a standard therapy, effectively prevents motor symptom fluctuations in people with Parkinson’s disease, results from two international Phase 3 studies show. The findings, “Once-Daily Opicapone Increases ON-Time in Patients with Parkinson’s Disease: Results from Two Phase…

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