News

Six months of daily tavapadon, as an oral add-on therapy to standard levodopa, significantly increased on time without troublesome dyskinesia, or involuntary body movements, in people in the late stages of Parkinson’s disease, according to top-line data from a Phase 3 study. Data from the trial, dubbed…

A three-week ketogenic diet, one low in carbohydrates and high in fat, supplemented with a specific type of fat — called medium chain triglycerides — showed no significant benefits in easing motor symptoms in a small group of people with Parkinson’s disease, a pilot trial has found. Whether this…

People with Parkinson’s disease who experience digestive issues or probable rapid eye movement (REM) sleep behavior disorder may be as much as twice as likely to develop symptoms of psychosis, a study found. Understanding what predicts early-onset psychosis in Parkinson’s can help doctors identify at-risk patients sooner, enabling them…

A Phase 1/2 clinical trial dubbed ASPIRO that’s testing Aspen Neuroscience’s ANPD001 — a stem cell therapy candidate designed to replace the nerve cells that are lost in Parkinson’s disease — has dosed its first patient. A first transplant was conducted at the Banner-University Medical Center Tucson by…

Sage Therapeutics’ dalzanemdor, formerly known as SAGE-718, an investigational oral medication for mild cognitive impairment (MCI) due to Parkinson’s disease, has failed to outperform a placebo in a Phase 2 study. Based on these top-line data from the trial, called PRECEDENT (NCT05318937), Sage will stop any further…

Updated exercise guidelines for those with Parkinson’s disease released by The Michael J. Fox Foundation (MJFF) now include Nordic pole walking as a suggested aerobic activity to help mitigate symptoms and improve everyday life. The exercise, a Finnish-derived low-impact total body walk, is also known as urban…

Having irritable bowel syndrome (IBS), a gastrointestinal disorder that may be linked to how the brain and gut communicate with each other, does not seem to increase a person’s risk for Parkinson’s disease, according to a new study of more than 400,000 people. In an analysis, the researchers “did…

Three biobehavioral scientists at Teachers College (TC), Columbia University are working on separate collaborative efforts in exercise, speech, and swallowing among Parkinson’s patients to potentially improve quality of life for the more than 10 million people estimated globally to be living with the progressive neurodegenerative disease. In honor…

The estate of a longtime supporter of the Norton Neuroscience Institute at Norton Healthcare has gifted the center $20 million to help expand programming and research in Parkinson’s disease and other movement disorders. The donation from the estate of Elizabeth Pahk Cressman, MD, PhD, will aid the Louisville,…

Cycling indoors on a stationary bicycle for two may improve the health and well-being of people with Parkinson’s disease and their care partners, a preliminary small study at the University of South Carolina suggests. The results were presented at the annual meeting of the American Academy of Neurology, which…