An ethics committee in Australia has cleared Gain Therapeutics to start a Phase 1 clinical trial testing GT-02287, the company’s experimental oral therapy for Parkinson’s disease associated with mutations in the GBA1 gene. GT-02287 now will become the first treatment candidate discovered with Gain’s proprietary platform, SEE-Tx, to…
Axim Biotechnologies has developed an assay to detect toxic clumps of the alpha-synuclein protein, a known biomarker of Parkinson’s disease, from a single teardrop. The company believes the noninvasive test, which can be run at the doctor’s office and provides faster results than other tear tests, could help…
The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has awarded a $4.5 million grant to Nine Square Therapeutics to advance the development of potential treatments for a genetic form of Parkinson’s disease. “The Michael J. Fox Foundation grant will go toward accelerating the identification of drug…
The findings of new research identifying the mechanism behind a familial form of Parkinson’s — one caused by a CHCHD2 gene mutation — suggest the potential to delay or perhaps prevent the disease’s development in people with the mutation, according to researchers. The team of scientists found this CHCHD2…
People with Parkinson’s disease commonly experience stigma associated with the disorder, and if clinicians are to provide proper care for patients, it’s crucial for them to be proactive about addressing such stigma. That’s the argument made by a team of scientists from the U.S. and Canada in a new…
An online artificial intelligence (AI)-powered test where users tap their fingers in front of a webcam may ultimately help rate the severity of Parkinson’s disease from afar and within minutes, a study suggests. The system performed almost as well as three expert neurologists and better than two primary care…
Researchers have built a map of how neurons wire up in the zebrafish brain to propel forward and steer movement, something people with Parkinson’s disease may have trouble with. As movement begins to be initiated, a region at the base of the brain known as the mesencephalic locomotor region…
A new blood test that assesses damage on a particular type of DNA may help in the early diagnosis of Parkinson’s disease, before symptoms start, a new study reports. “Currently, Parkinson’s disease is diagnosed largely based on clinical symptoms after significant neurological damage has already occurred,” Laurie Sanders,…
OM1 has launched a Parkinson’s disease premium dataset to expand real-world evidence on the progression of Parkinson’s progression and its treatments. The goal is to have a comprehensive view of the course of patients’ disease and contribute to accelerating research, assessing therapies’ effectiveness, and supporting procedures to…
A treatment that works to stimulate the brain using weak magnetic waves effectively eased symptoms in a mouse model of Parkinson’s disease, a new study reports. Researchers hope to start a small-scale study soon testing this treatment in people. “The technology is proven and it’s harmless and we want…
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