SandboxAQ has signed a $25 million research grant through an initiative of The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to develop new treatments that target the LRRK2 gene, mutations in which are one of the most common genetic causes of Parkinson’s disease. Under the partnership, which…
News
People with Parkinson’s disease who live in areas with measurable air pollution are at a heightened risk of hospitalization, according to a new analysis in the U.S. This work “provides critical information on whether air pollution could be used as a lever to reduce the risk of hospitalizations” with…
Analyzing vocal recordings could help in detecting Parkinson’s disease at early stages, according to a study that tested the idea using decades’ worth of recordings from celebrities who went on to develop the neurodegenerative condition. “This study shows that early patterns of [speech changes] are detectable up to 10…
Among adults in the U.K., poor hand grip strength is associated with an increased risk of developing Parkinson’s disease, especially among those who also have genetic risk factors for the neurodegenerative condition, according to a new report. Indeed, “compared with those with high [grip strength], low-[grip strength] individuals had…
Besides motor challenges, people with Parkinson’s disease have difficulty with motor imagery, or generating a mental representation of a movement, a study showed. That’s particularly true for the more affected side of the body. “Even when people with Parkinson’s think about movement, it’s different for their more affected side,”…
Metabolic syndrome, a cluster of conditions that can increase the risk of heart disease, diabetes, and stroke, is associated with a higher risk of developing dementia in people with Parkinson’s disease, according to recent research. “These findings advocate for comprehensive management of MetS [metabolic syndrome] as a pivotal strategy…
Changes in gut bacteria may be a useful marker to help diagnose Parkinson’s disease, according to a new analysis. The study, “Microbial biomarker discovery in Parkinson’s disease through a network-based approach,” was published in npj Parkinson’s Disease. The human digestive tract is home to billions of…
Inbrain Neuroelectronics has raised $50 million in funding to continue developing its brain-computer interface (BCI) technology using ultra-thin graphene electrodes, designed for more personalized treatment of people with Parkinson’s disease and other conditions. BCIs are implanted devices that can be used to decode and modulate brain activity.
A new partnership will work to develop customized assays to detect and quantify blood biomarkers to support the advancement of new treatments for neurodegenerative diseases, including Parkinson’s disease. Adx Neurosciences, which makes biomarker assays for neurodegenerative diseases, and Alamar Biosciences, a proteomics company with technology to detect…
Two newly identified brain pathways originating from the striosome — a cluster of nerve cells (neurons) in the striatum, a brain region that controls movement and motivation — may provide an additional layer of regulation, a mouse study found. The findings challenge scientists’ understanding of how the brain controls those…
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