Anxiety is common among people with Parkinson’s disease and contributes to a worse life quality for patients irrespective of motor symptom severity, according to a new German study. Nearly 40% of the patients in the small study were found to have clinically relevant anxiety — and those with more…
The presence of salt or a molecular crowd may make it more likely for the alpha-synuclein protein, which forms toxic clumps in the brains of people with Parkinson’s disease, to aggregate, or build up, into droplets, according to computer simulations run by researchers in India. Understanding how alpha-synuclein behaves,…
Among people in the early stages of Parkinson’s disease, a tool called trabecular bone score, or TBS, may help detect bone loss sooner than the bone mineral density (BMD) exam that’s the current gold standard, according to researchers. Specifically, the TBS tool may work better in assessing the degradation…
The U.S. Food and Drug Administration (FDA) said it needs more information before deciding whether to approve the apomorphine infusion pump SPN-830 for the treatment of Parkinson’s disease, according to a press release from the device’s developer Supernus Pharmaceuticals. In a complete response letter (CRL) to…
People with Parkinson’s disease are nearly twice as likely to experience delirium during hospital stays as hospitalized older adults without the neurodegenerative disease, according to a study from Newcastle University. Data showed that delirium, which often goes undocumented in Parkinson’s, was reported in as many as two-thirds of…
Treatment with lixisenatide, a medication approved for type 2 diabetes, significantly slowed the progression of motor symptoms in people with Parkinson’s disease in a Phase 2 clinical trial. Although gastrointestinal side effects such as nausea and vomiting were more common with the therapy, the findings support lixisenatide as a potential…
Scientists at the French Alternative Energies and Atomic Energy Commission (CEA) released the first images of a live human brain acquired with the world’s most powerful MRI scanner, the Iseult MRI machine. “With the Iseult project, a whole new world is opening up before our eyes, and we are excited…
A five-year project funded by a National Institutes of Health (NIH) research grant totaling nearly $1.9 million will study amyloid fibrils, protein clumps that are a hallmark of Parkinson’s disease and other neurodegenerative conditions. This work may shed new light on the disease-causing mechanisms related to these fibrils —…
People with REM sleep behavior disorder, a condition that often precedes Parkinson’s disease, frequently have mitochondrial DNA (mtDNA) damage, a study found. “Patients with REM sleep behavior disorder, both those who subsequently developed Parkinson’s disease and those who did not, had more mitochondrial DNA circulating in the cerebrospinal fluid…
Fecal microbiota transplant, a procedure that works to replace a person’s gut bacteria with gut bacteria from a healthy donor, may help ease motor symptoms of Parkinson’s disease, a small clinical trial found. Transplant “offers the advantages of being considered safe based on experience in other indications, and being…
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