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In a new study entitled “VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson’s Disease” scientists discovered that loss of the VPS35 protein expression in Parkinson’s disease interferes…

While scientists already know that the basal ganglia of the brain is related to movement disorders such as Parkinson’s disease and Huntington’s disease, this structure has always been difficult to study.  This is because the basal ganglia is a very small part of the brain located deep inside its anatomy and the various pathways…

Researchers at the University of Pennsylvania recently reported a new technique based on nanopores for the study of protein structure. The technique can potentially be applied in the study of protein aggregation that occurs in neurodegenerative disorders like Parkinson’s disease. The study was published in the journal…

In a new study entitled “Identification of neurodegenerative factors using translatome–regulatory network analysis” scientists at Rockefeller University identified two new proteins with key roles in Parkinson’s disease. The study was published in the journal Nature Neuroscience. Parkinson’s disease is a progressive degenerative disease of…

Dr. Michel Goedert from the Laboratory of Molecular Biology, Medical Research Council in the United Kingdom recently published in the journal Science a review on the mechanisms underlying Parkinson’s and Alzheimer’s diseases and their similarity to prion diseases. The study is entitled “Alzheimer’s…

The battle against Parkinson’s disease may be getting sweeter, with a new study underway seeking to understand if concentrated chocolate supplements could help alleviate the disease’s symptoms. A team of researchers from Dresden University of Technology, Germany, are busy conducting tests on 30 participants to further understand the benefits of phenylethylamine, a compound found…

Four years ago, in 2011, science journalist Jon Palfreman went to see his physician about the tremors he had been experiencing in his left hand. It was then, at 60 years of age, that Jon found out he already had Parkinson’s disease, a neurodegenerative disorder that causes a gradual loss…

Clinical stage biopharmaceutical company, Anavex Life Sciences Corp., recently announced that it received a research grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to fund the advancement of ANAVEX 2-73 – a candidate drug for Parkinson’s…

A multidisciplinary team of researchers from the Sheffield Institute of Translational Neuroscience (SITraN), in collaboration with scientists from the University of York, have recently released results from a study that supports the fast-tracking of the drug ursodeoxycholic acid (UDCA), which has already been in use for decades to…

Recently, researchers from the National Institutes of Health’s (NIH) National Institute of Neurological Disorders and Stroke (NINDS) released results from X-ray crystalography analysis of the the neuropeptide hormone neurotensin, which has been shown to be involved in Parkinson’s Disease (PD).  Their research resulted in the first images showing how…