News

An investigational compound called ITI-214, which is being investigated in clinical trials for Parkinson’s disease, may also be effective in strengthening the heart, according to an animal study recently published in the journal Circulation. ITI-214, being developed by Intra-Cellular Therapies, is a potent and selective inhibitor of an enzyme known…

The European Medicines Agency (EMA) endorsed an imaging test that can help in identifying Parkinson’ patients with early stage disease but likely to progress quickly — people who might be best suited to taking part in clinical trials. Development of this clinical assessment tool — which targets disease biomarkers —…

A new device that uses just a breath sample might, in the future, help diagnose early-stage Parkinson’s patients or identify those who may be at risk, according to researchers.   The innovative technology, developed by researchers at the…

Getting the perspective of Parkinson’s disease patients on their motivations and experiences participating in clinical trials can help increase recruitment and retention of future studies, a report suggests. Although preventable, one of the most common reasons Phase 2 or 3 trials fail is because not enough patients participate.

Longevity Biotech announced plans for a clinical study aiming to identify potential blood-based markers of inflammation that originates in the immune system, biomarkers that may work to better diagnose Parkinson’s and recognize the disease’s different stages. The study, being run with the support of The Michael J. Fox Foundation for…

Athletes playing contact sports for longer than eight years are six times more likely to develop Lewy body disease — a neurodegenerative disorder causing Parkinson’s-like symptoms — compared to those playing football, ice hockey or boxing for fewer years, a study reports. Its authors suggest that years of continual injury…

The LRRK2 gene may play an important role in nonhereditary Parkinson’s disease, not just the familial form as previously thought, researchers at the University of Pittsburgh School of Medicine​ have discovered. “This discovery is extremely consequential for Parkinson’s disease because it suggests that therapies currently being developed for a small…

One of the most promising therapeutic avenues for Parkinson’s disease is the use of stem cells to replace dopamine-producing neurons, the loss of which is a hallmark of the disease. This is the focus of a special issue on Parkinson’s disease published in the journal Stem Cells and…

A training program in which patients walk while listening to regular beats can improve the velocity and cadence of Parkinson’s disease patients, while reducing their risk of falling, a study shows. The study, “Rhythmic auditory stimulation for reduction of falls in Parkinson’s disease: a randomized controlled study,” was published…

Machine learning identifies individuals with reduced odor and taste sensitivity as people at risk for developing Parkinson’s disease, researchers from Italy report. The approach could be part of a noninvasive method to study early-onset Parkinson’s, the findings suggest. The study, “Comparative Motor Pre-clinical Assessment in Parkinson’s…