News

Researchers have discovered a way to block the spread of alpha-synuclein between neurons, which is believed to be at the core of the progression of the neurodegeneration seen in people with Parkinson’s disease. Interestingly, the drug that was able to block the spread and prevent neuron death is currently in clinical trials…

A new device that may improve the autonomy and quality of life of patients with Parkinson’s disease will be tested in a 19-month study that combines the products and skills of two companies, Aguettant and  French company Biocorp. The collaborative study, part of the APOKONNECT project, will be funded…

 Global Kinetics Corporation, specialized in developing health technology for people with Parkinson’s disease, has received premarketing clearance from the U.S. Food and Drug Administration (FDA) for the next generation of its wrist-worn Personal KinetiGraph (PKG) system. The PKG records movement symptoms of the Parkinson’s wearer, provides programmed medication…

The 4th World Parkinson Congress, held in Portland, Oregon, on Sept. 20-23, opened each day with a Hot Topics session, with the general public invited to listen to research presentations of particular interest. Topics ranged from complex scientific studies to children’s books, and a few of them caught…

Swedish researchers report that the massive burden of prioritizing visual stimuli from our environment lies with the the superior colliculus area of the brain. This ancient part of the brain may provide clues regarding the mechanisms leading to Parkinson’s disease, where patients often have impaired eye movement. The Karolinska Institute research paper, “Spatiotemporal interplay between…

The Parkinson’s research field is ready for precision medicine, four Parkinson’s experts stated in an editorial, suggesting that a switch from traditional disease concepts based on clustering of symptoms should be replaced by disease profiles built on knowledge of genetic and molecular changes. The editorial, “Parkinson’s…

Researchers may have found a test to diagnose neurological disorders such as Parkinson’s disease earlier, according to a new study published in the journal Physical Review Applied. The study, “Fluctuations in Protein Aggregation: Design of Preclinical Screening for Early Diagnosis of Neurodegenerative Disease,” was conducted by Giulio Costantini, from…

Recent research has shed light on the pathology of Parkinson’s disease by explaining how alpha-synuclein, a protein closely related to the disease, functions in a normal human brain. Findings may contribute to the design of future novel and appropriate therapies for Parkinson’s disease. The study, “Structural Basis Of Synaptic Vesicle Assembly…

NeuroDerm has started enrolling Parkinson’s disease (PD) patients in iNDiGO, a Phase 3 clinical trial evaluating the effectiveness of ND0612L, the company’s levodopa/carbidopa (LD/CD) subcutaneous liquid formulation. Levodopa and dopamine agonists, the first line of defense against Parkinson’s disease, are drugs commonly used to improve and control the symptoms of tremor, muscular…

A recent study suggests that a genetic mutation that disrupts a protein involved in the degradation of biological material within neurons allows waste products to accumulate, contributing to the pathology of Parkinson’s disease. Mutations in this protein, Vps35, have been associated with Parkinson’s disease, but until now, it was not…