Alpha-synuclein in saliva may be a potential biomarker for Parkinson’s disease, according to a recent review article, but more research is necessary to determine its reliability as a possible screening approach. The study with that finding, “Salivary alpha‑synuclein as a biomarker for Parkinson’s disease: a systematic review,” was…
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Alpha-arbutin — an antioxidant found in plants such as blueberry bush — may restore mitochondrial function in nerve cells and ease the motor disabilities associated with Parkinson’s disease, according to a preclinical study from China. Its results point to alpha-arbutin as a potential therapeutic compound for Parkinson’s and other…
Low vitamin D levels are associated with a greater tendency for falls, sleep problems, anxiety, and depression in people with Parkinson’s disease, according to a recent study. The findings, “Relationship between 25‐Hydroxyvitamin D, bone density, and Parkinson’s disease symptoms,” were published in the journal Acta…
Dopaminergic neurons — nerve cells gradually lost to Parkinson’s progression — that contain an enzyme called aldehyde dehydrogenase 1A1 are essential for acquiring the motor skills needed for proper movement in given situations, a mouse study reports. The research, “Distinct connectivity and functionality of aldehyde dehydrogenase 1A1-positive nigrostriatal dopaminergic…
Under-the-skin infusions of low-dose apomorphine using a wearable device called h-Patch may help in avoiding off periods and improving motor function in Parkinson’s patients, Valeritas, the technology’s developer, reports. A preclinical study found that apomorphine delivered using h-Patch could be detected in the blood within two hours, with a…
Women with Parkinson’s are more likely than men to have disease-related complications within five years of diagnosis and more likely to access healthcare services sooner, findings from a Dutch study suggest. The study, “Sex-Specific Patient Journeys in Early Parkinson’s Disease in the Netherlands,” was published in Frontiers in Neurology.
The Parkinson’s Foundation has added three Centers of Excellence to its international network of expert care providers for Parkinson’s disease patients. The new centers are the University of Colorado Movement Disorders Center, Jefferson Health’s Comprehensive Parkinson’s Disease & Movement Disorder Center, and Indiana University…
Scientist Wenquan Zou, MD, PhD, has received a two-year grant to develop a non-invasive skin test for diagnosing Parkinson’s disease, Alzheimer’s disease, and other neurodegenerative disorders. Diagnosing these disorders currently requires invasive analysis, either by imaging brain tissue or analyzing the cerebrospinal fluid (CSF) — the…
An online survey by the nonprofit group PMD Alliance found that care partners are more likely to report Parkinson’s disease-related non-motor symptoms than are patients themselves, and to feel more affected by them. These responses underscore the need for better recognition and education about Parkinson’s non-motor symptoms, many of…
A virtual reality game being created by engineering students, called “Overcome,” aims to offer Parkinson’s patients safe and fun ways of taking part in rehabilitation sessions that might preserve walking and mobility skills. Though players of all ages may find the game entertaining, “Overcome” is intended for adults…
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